Project Grant R01AG097950
Award Date 9/1/26
Completion Date 5/31/31
Dollars Obligated $657K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Chicago, IL 60612, USA
Similar Awards
- The National Institute on Aging awarded The General Hospital Corporation (Massachusetts General Hospital) $129,330 on August 15, 2026, under the Aging Research program (CFDA 93.866) to develop artificial intelligence techniques for identifying cerebral amyloid angiopathy at early disease stages using multimodal MRI sequences. The recipient will integrate accessible MRI sequences—T1-weighted, T2-weighted, T2*-weighted gradient echo, fluid-attenuated inversion recovery, and diffusion imaging—to...
- This $1,246,362 project grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) to Rush University Medical Center aims to elucidate the morphology and compositional changes of the perivascular pia mater (PVS PIA) in the human brain across aging and Alzheimer's disease. The 3-year project will leverage clinical and pathological data from the Rush Religious Orders Study and Memory and Aging Project to map PVS PIA anatomy using advanced microscopy techniques. Key...
- The National Institute on Aging awarded Marquette University $309,000 on May 15, 2026, under the Aging Research program (CFDA 93.866) to conduct longitudinal imaging studies in a preclinical Alzheimer's disease model aimed at identifying early biomarkers of cognitive decline. The project uses in vivo calcium imaging of prefrontal cortical neuronal ensembles and two-photon imaging of amyloid-beta deposits in a transgenic rat model to track changes in genetically defined excitatory and...
- The National Institute on Aging awarded the University of Wisconsin-Madison $427,625 on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate cerebral small vessel disease pathways in vascular contributions to cognitive impairment and dementia and Alzheimer's disease using ferumoxytol-enhanced MRI. The research will employ novel microvascular biomarkers including quantitative characterization of vascular density and hemodynamic measures of microvascular pulsatility...
- The National Institute on Aging awarded Indiana University Indianapolis $109,795 on August 20, 2026, under the Aging Research program (CFDA 93.866) to evaluate amyloid dynamics and cerebral amyloid angiopathy burden. The project examines amyloid plaque redistribution and cerebral amyloid angiopathy development through genetic and pharmacological methods, and tests whether dietary and exercise interventions mitigate cerebral amyloid angiopathy burden. The research evaluates glial-based mechanisms...
- The National Institute on Aging awarded New York University $6.203 million on September 15, 2025, under the Aging Research program (CFDA 93.866) to examine peripheral immune markers and vascular dysfunction as contributors to cognitive decline and Alzheimer's disease. The research integrates circulating biomarkers—platelet aggregation, neutrophil activity, and proteomic data—with advanced imaging to assess associations between vascular and immune dysfunction and cerebrovascular burden, amyloid...
- The National Institute on Aging awarded the University of California, Berkeley $549,260 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop advanced large language model-based AI tools that enhance precision in predicting Alzheimer's disease pathology and cognitive outcomes. The research addresses critical gaps in precision medicine for Alzheimer's disease, particularly the need to capture patient heterogeneity, accurately identify treatment candidates for...
- The National Institute on Aging awarded The General Hospital Corporation (Massachusetts General Hospital) $660,000 on March 15, 2026, under the Aging Research program (CFDA 93.866) to develop deep learning–based image registration and morphometric analysis tools for structural MRI-derived biomarkers in Alzheimer's disease diagnosis. The project aims to improve the sensitivity and accessibility of longitudinal morphometric metrics derived from T1-weighted structural brain MRI scans—a non-invasive...
- The National Institute on Aging awarded $526,607 to Wake Forest University on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop computational imaging frameworks that integrate neuroimaging with multi-omics data to identify Alzheimer's disease subtypes and model neurodegenerative progression with calibrated uncertainty. The project, titled "Neuroimaging Multi-Omics Fingerprints for Subtyping and Uncertainty-Aware Prediction of Alzheimer's Disease," will...
- The National Institute on Aging awarded New York University $466,125 under the Aging Research program (CFDA 93.866) on January 15, 2026, to develop innovative magnetic resonance imaging analysis tools for identifying microstructural biomarkers of skeletal muscle health across the lifespan. The project, titled "(Micro)structural Biomarkers of Skeletal Muscle Health Across the Lifespan," addresses sarcopenia—a leading cause of disability and mortality in aging populations—by creating...