Project Grant R01AG096437
Award Date 9/1/25
Completion Date 5/31/30
Dollars Obligated $645K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
- This $326,797 Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) aims to identify proteomic (protein-based) biomarkers that can predict risk of cognitive impairment in individuals with type 2 diabetes. The primary goal is to use proteomic analyses to discover plasma protein differences and networks associated with newly diagnosed mild cognitive impairment in this population. The project will also examine how these proteins relate to preclinical...
- This Project Grant award, valued at $2,380,018.00, was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to the Regents of the University of Michigan. The overarching goal is to investigate the influence of cumulative hyperglycemia, type 2 diabetes management, and vascular risk factors on cognitive decline and Alzheimer's disease and related dementias (ADRD) risk. The research team will leverage pooled cohort studies and individual participant data meta-analysis to...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $167,940 project grant to The Children's Hospital Corporation (Boston Children's Hospital) to elucidate the neuronal mechanisms underlying cognitive resilience to Alzheimer's disease. The project, awarded on August 15, 2025, aims to (1) determine if the MEF2 transcription factors mediate survival of specific neuronal subtypes vulnerable to Alzheimer's pathology, (2) assess whether...
- The National Institute on Aging (NIA) awarded a $429,000 Project Grant (CFDA 93.866 - Aging Research) to Northeast Ohio Medical University (Neomed) to evaluate the role of acetylation on brain proteome dynamics in a mouse model of Alzheimer's Disease (AD) and type 2 diabetes mellitus (T2DM). The 2-year project aims to quantify proteome and acetylome dynamics in the hippocampus and frontal cortex of diet-induced diabetic and non-diabetic AD mice to determine the effect of T2DM-related...
- The National Institute on Aging (NIA), through its Aging Research federal grant program (CFDA 93.866), awarded a $636,342 Project Grant to Trustees of Boston University (doing business as Boston University Medical Campus) to conduct research on normal and pathological brain aging. The grant, with a performance period from August 1, 2025 to April 30, 2030, will support a multiscale modeling and empirical study of progressive myelin dystrophy, loss of synapses, and neuronal hyperexcitability in...
- The National Institute on Aging (NIA) has awarded a $640,906 project grant under CFDA 93.866 Aging Research to the University of Wisconsin-Madison to conduct research on "Elucidating Cerebrovascular Disease Pathways to Cognitive Decline with Vascular Neuroimaging." The 5-year project aims to utilize advanced neuroimaging techniques to understand the vascular contributions to cognitive impairment and dementia (VCID), and assess their relationship to Alzheimer's disease proteinopathy....
- This $2,365,042 Project Grant was awarded by the National Institute on Aging (NIA) under the Aging Research Federal Grant Program (CFDA 93.866) to conduct research on the biological underpinnings of Alzheimer's disease and related dementias (ADRD). The research aims to better characterize the interplay between biological markers of neurodegeneration, vascular, nutritional, and inflammatory systems, and their interface with social and economic factors, by leveraging cross-national comparisons...
- The National Institute on Aging (NIA) awarded a $842,175 Project Grant under the Aging Research program (CFDA 93.866) to the J. David Gladstone Institutes in San Francisco, CA. The grant, awarded on December 15, 2024, will fund research to explore the role of the NOX2 enzyme in mediating Alzheimer's disease (AD) pathologies, including network hyperactivity, glucose hypometabolism, and accumulation of amyloid-beta and tau proteins. The research aims to assess the therapeutic efficacy of a novel...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $770,558 project grant to Wake Forest University Health Sciences (WFUHS) to establish connections between Alzheimer's disease (AD)-related genomic markers and neuroimaging phenotypes. The objective is to determine the heterogeneity of AD subtypes and their association with the clinical onset of dementia. The project aims to develop data-driven computational models using multi-modal...
- The National Institute on Aging (NIA) awarded a $713,723.32 Project Grant under the Aging Research Federal Grant Program (CFDA 93.866) to the Albert Einstein College of Medicine in Bronx, NY. The award, effective from February 1, 2025 to January 31, 2028, will support research on the influence of neighborhood characteristics, both objective and subjective, as well as GPS-based personal activity space measures, on cognitive decline, Alzheimer's disease and related dementias (ADRD), and...