Project Grant R01AG093616
- Federal Project Grant Award Summary New York University School of Medicine received a $466,125 Project Grant award from the National Institute on Aging (Aging Research program, CFDA 93.866) effective January 15, 2026, with completion targeted for December 31, 2027. The award supports development of innovative magnetic resonance imaging (MRI) analysis tools and frameworks designed to identify microstructural and structural biomarkers of skeletal muscle health across the lifespan. The research...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Spaulding Rehabilitation Hospital Corporation a project grant of $665,970 under the Aging Research program (CFDA 93.866), effective August 1, 2025, with a completion date of May 31, 2030. This research initiative delivers network medicine-based discovery research aimed at identifying disease-modifying therapeutic approaches for knee osteoarthritis (KOA), a condition affecting more than 30 million individuals in the...
- Federal Project Grant Award Summary The National Institute on Aging awarded $698,690 to the University of Wisconsin-Madison under its Aging Research program (CFDA 93.866) effective February 1, 2026, through January 31, 2031. This Project Grant supports basic research investigating the molecular mechanisms underlying fiber type-specific skeletal muscle dysfunction in aging populations. The research project will deliver scientific findings and data products examining how aging affects slow...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $694,824 Project Grant to the University of California, San Francisco on August 1, 2025, under the Aging Research program (CFDA 93.866) to support a five-year research project extending through May 31, 2030. The award funds a scientific investigation titled "Triangulating Mechanisms of Microbiome-Joint Crosstalk," which examines the interorgan communication between the gut microbiome and joint tissues in the...
- Federal Grant Award Summary The National Institute on Aging awarded a $116,710 Project Grant to the University of Connecticut, Office Sponsored Programs, effective August 1, 2025 through April 30, 2030, under the Aging Research program (CFDA 93.866). This career development award supports research to establish sex-specific determinants of muscle quality in older adults, with particular focus on understanding how males and females experience different mechanisms of sarcopenia—the age-related loss...
- Federal Project Grant Award Summary The National Institute on Aging awarded a $673,012 Project Grant to the University of Massachusetts, beginning August 15, 2025, and extending through July 31, 2030, under the Aging Research program (CFDA 93.866). This research project will investigate the neuromechanical bases for increased energy cost of walking in older adults, a significant contributor to age-related mobility loss and a major public health concern. The research will examine how...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $412,500 Project Grant to the University of South Florida (USF) under the Aging Research program (CFDA 93.866) for a two-year research initiative running from June 1, 2025, through May 31, 2027. This grant funds scientific research aimed at identifying novel biomarkers for early diagnosis and prognosis prediction of Alzheimer's disease (AD), a neurodegenerative condition affecting 5.5 million Americans. The project...
- Federal Grant Award Summary The University of Pennsylvania received a $109,076 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective November 27, 2025, with completion expected by May 31, 2030. This award funds research investigating the modulation of synovial mechanobiology to mitigate disease progression in osteoarthritis (OA), a condition affecting nearly 8% of the global population with particular burden among older adults. The...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded The Spaulding Rehabilitation Hospital Corporation a Project Grant totaling $639,997 under the Aging Research program (CFDA 93.866), effective May 15, 2025, with a completion date of March 31, 2030. This research initiative investigates the mechano-regulation of circulating extracellular vesicle cargoes to enhance knee joint health and address knee osteoarthritis (KOA), a condition affecting over 30 million older...
- Federal Project Grant Award Summary Vanderbilt University Medical Center received a $149,889 Project Grant award from the National Institute on Aging under the Aging Research program (CFDA 93.866) effective September 1, 2025, with completion targeted for May 31, 2030. This research initiative will develop and validate deep learning (DL) and artificial intelligence (AI) approaches to identify epigenetic factors associated with early-stage osteoporosis and osteopenia through analysis of computed...
The National Institute on Aging awarded a $666,504 Project Grant to the University of Kentucky Research Foundation on February 1, 2026, under the Aging Research program (CFDA 93.866). This five-year research initiative, extending through January 31, 2031, focuses on developing and validating noninvasive magnetic resonance imaging (MRI) biomarkers to assess muscle quality in older adults with knee osteoarthritis. The project will evaluate advanced MRI techniques, specifically T1 Rho MRI and diffusion tensor imaging, by correlating noninvasive imaging measurements with direct tissue assessments obtained from quadriceps muscle biopsies to establish reliable biomarkers for detecting muscle dysfunction. The research deliverables include establishing validated, noninvasive MRI biomarkers that characterize altered muscle quality and fiber size in individuals with knee osteoarthritis, and determining the relationship between these imaging measures and functional outcomes including muscle strength and physical performance. By identifying specific cellular and acellular sources of poor muscle quality in this population, the project addresses a critical gap in understanding quadriceps muscle pathology beyond cartilage erosion, with the ultimate goal of enabling future targeted therapeutic interventions for this prevalent cause of disability among older adults.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $666.5k | 1/23/26 |