Project Grant R01AG087264

Award Date 4/1/25
Completion Date 3/31/30
Dollars Obligated $1.2M
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Lebanon, NH 03756, USA
Similar Awards
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $2,433,859 supports research at The Johns Hopkins University to investigate age-related hearing loss and cognitive decline. The key objectives are to study the molecular, cellular, and connectivity changes in the central auditory system during normal aging and Alzheimer's disease, with the goal of developing targeted therapeutic strategies. The research integrates single-cell...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a study to evaluate the associations between hearing loss and cognitive and brain health outcomes in middle-aged adults. The $262,975 grant, awarded to Kaiser Foundation Hospitals/Kaiser Foundation Research Institute, will fund research utilizing data from the Coronary Artery Risk Development in Young Adults (CARDIA) study. The project aims to: 1) test whether hearing loss is associated...
This $783,083 Project Grant, awarded by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), aims to understand the effects of cochlear implants and hearing aids on cognitive function in older adults with age-related hearing loss. The study will compare real-world outcomes across six groups: cochlear implant users, hearing aid retainers, and normal hearing controls, both with and without mild cognitive impairment. The primary outcome measure is an ecological...
The National Institute on Aging (NIA) awarded a $349,016 Project Grant under the Aging Research federal grant program (CFDA 93.866) to The University of Texas at San Antonio (UTSA) to conduct research on the mechanisms linking auditory perception and high-level cognition in normal aging. The 5-year project will use a multimodal approach including structural equation modeling, electroencephalography (EEG), and psychophysiological measures to test hypotheses about attention control and sensory...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $245,625 to The Johns Hopkins University to investigate the role of language acculturation in the relationship between hearing loss and cognitive decline among Hispanic adults in the United States. The 2-year project aims to: 1) examine whether the association between hearing loss and cognitive decline over 6 years differs by language acculturation levels, 2) investigate the link...
This $477,660 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA 93.173 "Research Related to Deafness and Communication Disorders" program, will support research to investigate age-related declines in perceptual decision-making processes that limit speech recognition and memory in noisy environments for older adults. The key objectives are to: 1) characterize how older adults accumulate sensory evidence more slowly...
This $443,758 Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) to Northwestern University aims to evaluate the use of over-the-counter (OTC) hearing aids for improving communication outcomes in older adults with mild cognitive impairment (MCI) or early Alzheimer's disease and related dementias (ADRD). The study will run from September 2023 to August 2025. Under this award, Northwestern University will lead a randomized trial to compare the communication...
This Project Grant award of $111,313.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research to investigate aging-related deficits in auditory temporal fidelity and spatial hearing abilities. The award recipient, The Regents of the University of Colorado, doing business as University of Colorado-Denver, will conduct this research from Sep 30, 2024 through...
This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $2,262,375 to the University of Massachusetts to conduct a study on using wearable devices and artificial intelligence (AI) to develop digital biomarkers for early detection of Alzheimer's disease. The project aims to deploy consumer wearables for sleep, heart rate, and activity monitoring in a cohort of older adults at high genetic risk for Alzheimer's. It will validate the wearables against...
This $193,750 federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) supports research on the neural dynamics and circuits in the auditory cortex that enable implicit learning of complex sounds in mice. The project aims to identify the specific neural mechanisms and causal links between neuronal characteristics and implicit auditory learning by...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a research study to assess the relationship between auditory test performance and the progression of Alzheimer's disease pathology. Specifically, the $1,183,821 award to Dartmouth College will examine whether peripheral or central auditory processing deficits correlate with the accumulation of amyloid-beta plaques and tau tangles in the brain over time. The study will leverage an existing longitudinal cohort and leverage PET imaging, neurocognitive testing, and biofluid sampling to comprehensively characterize Alzheimer's disease biomarkers. The goal is to determine if auditory tests could serve as predictive or monitoring tools for Alzheimer's disease progression, potentially leading to new interventions targeting hearing loss as a risk factor. The 5-year project period runs from April 1, 2025 to March 31, 2030.

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