The University of Texas Health Science Center at San Antonio (UTHSCSA) was awarded a $1,339,916 Project Grant from the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866). The grant, awarded on September 22, 2024, will support research to explore the impact of leptin modulation on healthspan and lifespan. Specifically, the research aims to determine whether aging-associated hyperleptinemia accelerates cellular senescence and impairs healthspan and lifespan, assess the effects of reducing leptin on cellular senescence, healthspan, and lifespan, and elucidate the underlying mechanisms mediating leptin-driven cellular senescence. The project is scheduled for completion by July 31, 2029.
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