Project Grant R01AA032899
- The National Institute on Alcohol Abuse and Alcoholism awarded the Seattle Institute for Biomedical and Clinical Research $474,762 on May 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate how blast-induced traumatic brain injury and chronic alcohol use interact to accelerate neurodegeneration and Alzheimer's disease and related dementia in preclinical rodent models. The research examines the glymphatic system—the brain's waste clearance mechanism—as a potential...
- The National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health within the Department of Health and Human Services, awarded $682,736 to Beth Israel Deaconess Medical Center, Inc. on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate myeloid-derived suppressor cells (MDSCs) in alcohol-associated steatohepatitis. The award funds research characterizing MDSC phenotypes and immunoregulatory capacity in alcohol-associated hepatitis...
- The National Institute on Alcohol Abuse and Alcoholism awarded Yale University $100,228 under the Alcohol Research Programs (CFDA 93.273) on October 27, 2026, to investigate the neurobiological mechanisms underlying the co-occurrence of alcohol use disorder and post-traumatic stress disorder. The project examines how stress exposure disrupts excitation-inhibition balance in the medial prefrontal cortex, driving increased alcohol consumption and heightened motivation for alcohol use. Using single...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA), a division of the Department of Health and Human Services National Institutes of Health, awarded Yale University $663,419 on August 11, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate liver sinusoidal endothelial cell (LSEC) inflammation in alcohol-associated liver disease. The research addresses mechanisms by which alcohol disrupts LSEC homeostasis through two converging pathways: IL6 trans-signaling mediated...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $167,500 in Project Grant funding to the University of Massachusetts Medical School on September 17, 2025, through the Alcohol Research Programs (CFDA 93.273) for a research study investigating sex differences in excessive alcohol use patterns across young adulthood and middle age. The research will utilize longitudinal data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) to examine how...
- The National Institute on Alcohol Abuse and Alcoholism awarded Baylor College of Medicine $719,068 on August 15, 2026, under the Alcohol Research Programs (CFDA 93.273) to develop an augmented reality smartphone application for treating alcohol use disorder in veterans. The award funds development of an AR app that addresses a critical gap in behavioral therapy for alcohol use disorder by enabling cue-exposure treatment in real-world environments. The application delivers virtual alcohol-related...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Pittsburgh $903,936 on September 20, 2025, under the Alcohol Research Programs (CFDA 93.273) to investigate mechanisms of alcohol's effects on prefrontal cortex circuits, with performance through July 31, 2030, in Pittsburgh, Pennsylvania. The research examines how vasoactive intestinal peptide–expressing inhibitory interneurons (VIP-INs) in the prefrontal cortex modulate drinking behavior and affective changes in...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Medical University of South Carolina $488,077 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate molecular and functional adaptations in the nucleus reuniens, a midline thalamic region implicated in alcohol-related cognitive deficits. The research addresses how chronic alcohol exposure produces cognitive dysfunction that impairs treatment outcomes and increases relapse risk. The project will...
- The National Institute on Alcohol Abuse and Alcoholism awarded Virginia Commonwealth University $739,964 on September 11, 2025, under the Alcohol Research Programs (CFDA 93.273) to support research dissecting the co-occurrence of alcohol use and problems with suicidal thoughts and behaviors through genetic liability and neurocognitive mechanisms. The research explores aggregate genetic liability and neurocognitive mechanisms underlying the co-occurrence of alcohol use disorders and suicidal...
- The National Institute on Alcohol Abuse and Alcoholism awarded Cedars-Sinai Medical Center $1.235 million under the Alcohol Research Programs (CFDA 93.273) on September 10, 2025, to investigate the role of prohibitin 1 (PHB1) in ethanol's sensitizing effect on colorectal liver metastasis. Research will examine how excessive alcohol intake depletes hepatocyte nuclear and cytosolic PHB1, increasing matrix metalloproteinase-7 (MMP-7) expression and rendering the liver susceptible to colorectal...
The National Institute on Alcohol Abuse and Alcoholism awarded Western Institute For Veterans Research $1,553,315 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to assess the impact of housing interventions on alcohol-related harms among veterans experiencing homelessness or housing instability. The project will analyze linked longitudinal data spanning more than a decade, combining participation records from the Supportive Services for Veteran Families (SSVF) program with veteran electronic health records to determine whether housing-focused interventions improve alcohol use outcomes and reduce alcohol-related treatment needs and mortality. The research addresses a documented gap: while prior studies demonstrate that SSVF improves veteran housing outcomes, healthcare costs, and all-cause mortality, the program's specific effects on alcohol use disorder and alcohol-related harms remain unstudied, despite three in five homeless adults reporting a history of alcohol use disorder. Performance occurs in Salt Lake City, Utah, with a period of performance from September 1, 2026, through August 31, 2029. The award is structured as a Project Grant under the NIAAA Alcohol Research Programs, which supports research to develop fundamental knowledge applicable to improved treatment methods and prevention strategies for alcoholism and alcohol-related problems.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.6m | 8/31/26 |