Project Grant R01AA031657
- This federal Project Grant award of $119,253 from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) supports research to investigate the impact of third trimester alcohol exposure on memories encoded by sharp-wave ripples in the hippocampal-retrosplenial cortex circuit. The research will use a mouse model, in vivo electrophysiology, and optogenetics to examine how this alcohol exposure affects key features of sharp-wave ripples, such as amplitude...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $550,417 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Texas at Austin. The grant, effective September 1, 2025 through May 31, 2030, supports research to investigate how heavy alcohol exposure in aging individuals leads to impaired microglia function, neurodegeneration, and cognitive deficits. The study aims to determine whether dysregulated neuroimmune and microglia responses are...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $412,125 Project Grant under the Alcohol Research Programs (CFDA 93.273) to The Research Foundation For The State University Of New York to study the impact of prenatal alcohol and methadone exposure on the regulation of dopamine signaling and synaptic plasticity in the basolateral amygdala. The two-year project aims to determine how the combined exposure to prenatal alcohol and methadone alters social and non-social...
- This $128,481 Project Grant awarded by the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 Alcohol Research Programs) aims to determine the effect of pharmacological, genetic, or activity-based interventions to restore the neurogenic response to environmental enrichment in a mouse model of prenatal alcohol exposure. The key research objectives are to: Evaluate the therapeutic potential of the antidepressant fluoxetine to restore the neurogenic effects of environmental...
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) provides $248,959 to The Medical College of Wisconsin, Inc. to conduct research on the reciprocal relationship between alcohol use and brain function in adolescents and young adults. The 5-year project aims to assess how neurocognitive mechanisms of decision-making and risk-taking in adolescence contribute to alcohol use initiation, escalation, and maintenance,...
- This Project Grant award, valued at $2,250,249.00 and funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports a research project conducted by the University of California, San Diego (UCSD) to investigate brain features associated with alcohol use disorder (AUD). The project aims to employ longitudinal multi-parametric magnetic resonance imaging (MRI) to assess baseline brain characteristics and changes following alcohol...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), has awarded a $410,413 Project Grant to Rutgers, The State University of New Jersey for the project "BLOOD BRAIN BARRIER DYSFUNCTION IN CHRONIC ALCOHOL USE DISORDER". The project aims to utilize a non-invasive MRI technique to map and determine the correlates of blood-brain barrier alterations in individuals with a history of severe chronic alcohol use disorder. The...
- This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA, CFDA 93.273 Alcohol Research Programs) provides $647,330 to Wake Forest University Health Sciences to conduct research on the role of epigenetics in predisposing the brain to risky alcohol use. The researchers will perform a longitudinal genome-wide DNA methylation analysis of the rhesus macaque dorsolateral prefrontal cortex to identify biomarkers associated with future alcohol drinking levels. The goal...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $136,236 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Washington on January 25, 2025. The grant project aims to investigate the synergistic effects of chronic alcohol use and pathological tau expression in a preclinical model, in order to better understand the neurodegeneration processes underlying Alzheimer's disease and related dementias (ADRD). Specifically, the research will...
- This Project Grant award, totaling $560,108.00 and spanning September 15, 2025 to August 31, 2030, was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The purpose of the project is to investigate the neurocognitive mechanisms that promote resilience to alcohol use disorder (AUD) in individuals with a family history of AUD. Specifically, the research will examine how attentional abilities may...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $733,704 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Lovelace Biomedical Research Institute in Albuquerque, New Mexico. The grant, titled "Multimodal Imaging of Prenatal Alcohol Exposure: Mechanisms Underlying Spatial Navigation Memory Deficits in Children and Adolescents," will fund a study to advance understanding of the neurophysiological mechanisms underlying spatial memory deficits in children with prenatal alcohol exposure. The 5-year project, running from September 1, 2025 to June 30, 2030, will utilize functional MRI and magnetoencephalography to examine hippocampal circuitry and oscillatory brain activity associated with spatial navigation memory in 112 participants aged 8-14 years old. This research aims to provide foundational knowledge on how prenatal alcohol exposure alters brain function and identify potential treatments for spatial memory impairments.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $733.7k | 9/19/25 |