Project Grant R00DC021984
Award Date 9/2/25
Completion Date 8/31/28
Dollars Obligated $249K
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
North Andover, MA 01845, USA
Similar Awards
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $767,494 to the University of Miami to develop human inner ear organoid platforms for studying genetic hearing loss and vestibular disorders. The key objectives are to: 1) establish and optimize human induced pluripotent stem cell-derived 3D inner ear organoid systems from patients with...
- The federal Project Grant award of $111,321.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research conducted by President and Fellows of Harvard College (Harvard Medical School) to develop novel inner ear organoid models for studying hair cell development and Usher syndrome type 1F, a form of deaf-blindness. The research aims to overcome challenges in...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $387,500.00 to The Johns Hopkins University from January 1, 2025 to November 30, 2029 to elucidate the gene regulatory networks that control hair cell regeneration in zebrafish. The research aims to identify key transcription factors, such as SOX and SIX, that regulate the transition of support cells to a progenitor state capable of...
- This Project Grant award, titled "Epigenetic Mechanisms of Cochlear Damage and Repair," was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) federal grant program. The $652,216 award to Rutgers, The State University will support research to investigate the role of the CHD4 protein in maintaining hair cell identity and function in the cochlea. The 5-year project...
- This federal Project Grant award of $781,703, awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA 93.173 "Research Related to Deafness and Communication Disorders", supports research to better understand sensory development in human cochlear organoids. The goals are to define the developmental trajectories of key sensory cell types, test methods to increase the number of hair cells, and accelerate the maturation of hair cells and sensory...
- This federal Project Grant award for $486,750.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program. The grant supports research to explore the morphological changes and cell polarity mechanisms in supporting cells of the inner ear, which play a critical role in auditory function. The primary awardee, the Jackson Laboratory, a nonprofit biomedical research...
- This Project Grant award of $637,500.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173). The goal of the project is to understand the forward transduction that drives inner and outer hair cell stereocilia, as well as the reverse transduction that amplifies motion in the human cochlea, using a novel finite element modeling technique. The research will focus...
- The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $410,534 Project Grant to The Medical University of South Carolina (MUSC) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant, awarded on September 10, 2025, seeks to identify genetic modifiers that influence the penetrance of hearing impairment in the context of Endothelin receptor EDNRB deficiency. The research aims to address the role of the KCNJ16 gene, which...
- The National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), awarded a $589,393 Project Grant to Northwestern University to support research on the development of cochlear innervation. The goal is to elucidate how the neural circuit in the mammalian cochlea assembles during development, by altering the identity of certain cell types involved. Through this project, the researchers will...
- This Project Grant award of $670,318, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA 93.173 - Research Related to Deafness and Communication Disorders, will fund research to investigate the biological functions of the CHD7 gene and its role in the inner ear development pathology of CHARGE syndrome. The key objectives are to: 1) Establish human embryonic stem cell lines with specific CHD7 mutations to study their impact on gene/protein...