Project Grant Q184A080090

This $673,500 Project Grant from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism will fund Amygdala Neurosciences, Inc. to develop new, potent, selective, and reversible inhibitors of aldehyde dehydrogenase 2 (ALDH2) for the treatment of alcohol use disorder. The goal is to implement an innovative screening technology to discover novel compounds that reduce craving and alcohol consumption by selectively inhibiting ALDH2 in a reversible manner, avoiding...

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $399,048 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Rochester Institute of Technology (RIT) to examine behavioral and electrophysiological cue reactivity in young adult binge drinkers. The study will compare responses to uni- and multisensory alcohol and neutral cues that vary in degree of realistic appearance, and explore the effects of multisensory congruence on cue responses. The project...

Federal Grant Award Summary Research Triangle Institute (RTI International) received a $901,666 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective September 20, 2025, with completion targeted for June 30, 2030. The project aims to develop small molecule negative allosteric modulators (NAMs) of the RXFP3 receptor as novel pharmacological treatments for alcohol use disorder (AUD). RTI will optimize...

Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $413,496 to The Research Foundation for the State University of New York under the Alcohol Research Programs (CFDA 93.273) to conduct research on enhancing alcohol use disorder (AUD) recovery through comprehensive assessment of psychological well-being (PWB) in daily life. Awarded on September 20, 2025, with completion targeted for August 31, 2027, this project addresses a critical gap in...

Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Virginia $800,105 under the Alcohol Research Programs (CFDA 93.273) Project Grant program on September 20, 2025, with a completion date of August 31, 2028. This R61/R33 award supports the development and optimization of CARRI, a digital intervention designed to reduce alcohol-exposed pregnancy (AEP) risk among Native American women. The project systematically tailors and tests the...

Federal Grant Award Summary Brown University received a $733,137 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective September 18, 2025, with an ultimate completion date of August 31, 2030. The award supports a 12-week, double-blind, randomized controlled trial (RCT) evaluating probenecid as a therapeutic intervention for alcohol use disorder (AUD) in 120 individuals. The research builds on...

Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the Public Health Institute a Project Grant of $282,353 on September 16, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a secondary analysis examining the relationship between blood alcohol content (BAC) limit laws and alcohol-related outcomes. The two-year project, concluding August 31, 2027, will utilize causal inference methods and existing datasets spanning 1970-2024...

Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Massachusetts General Hospital $734,468 on September 23, 2025, under the Alcohol Research Programs (CFDA 93.273) to develop and pilot test Social Identity Mapping for Adolescents in Recovery (SIM-AIR), a novel adjunctive intervention module designed to improve treatment outcomes for adolescents with alcohol use disorders (AUD). The project, which runs through August 31, 2028, addresses a critical...

Federal Project Grant Award Summary RTI International received a $711,938 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 20, 2025, with completion targeted for August 31, 2030. The grant funds a Type 1 Hybrid Implementation Effectiveness Cluster Randomized Trial designed to test the efficacy and implementation of Better Informed Parents Keeping Adolescents Safe from Alcohol (BIPAS), a mobile...

Federal Project Grant Award Summary Real Recovery VR, Inc. received a $928,356 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective September 15, 2025, with completion targeted for August 31, 2026. The award funds development of a Virtual Reality (VR) platform designed for use by counselors treating patients with Alcohol Use Disorder (AUD). The platform aims to enhance evidence-based counseling...