Ucla-UCI center for eliminating cardio-metabolic disparities in multi-ethnic populations (UC end-disparities)

Active Project Grant Awarded Last action

Award ID
P50MD017366
Recipient
Awarding agency
Obligated
$55,295,048

Award facts

Completion date 88% complete
Originally
Funding
  • $51,809,567.00 Federal
  • $3,485,481.00 Non-federal
Place of performance
Los Angeles, CA 90024, USA

Award details come from USAspending.gov.

Description

Abstract
P50 UC end-disparities UC end-disparities will address the inequitable multilevel factors that promote cardiometabolic disease, including hypertension, diabetes, and complications such as atherosclerotic vascular disease and chronic kidney disease. These conditions are highly influenced by structural disadvantage and disproportionately affect low-income, minoritized, and other marginalized groups in the highly diverse and contiguous region of LOS angeles county (LAC) and orange county (OC) (combined population over 13M; > 46 states). The center will fill a GAP in the current efforts to advance health equity via a multilevel community-academic partnered approach to improve cardiometabolic related health outcomes in targeted LAC and OC latino, black, asian, pacific islander, and american indian communities, which have some of the highest rates of cardiometabolic risk factors and premature cardiovascular morbidity and mortality in the nation. UC end-disparities will function through three highly integrated cores and three inaugural center research projects across southern california, all supporting pilot awards and community catalyst awards, while leveraging synergies with key community-academic networks, community, public health, and health system stakeholders, regional networks of minority-serving institutions, centers at ucla and UCI for clinical and translational science, and methodologic leaders with expertise in health equity research, biostatistics, implementation science, and health information technology. The administrative core, investigator development core, and community engagement core will implement the following center objectives: 1) provide administrative and operational support for all activities and collaborate with the nimhd chronic disease disparities coordinating center; 2) develop the requisite community-academic research infrastructure to improve the health of the diverse multiethnic communities of LAC and OC through multilevel interventions; 3) broaden/enhance existing and new partnerships with communities to expand the pool of diverse participants in research and recipients of findings for UC end disparities and related funded entities; 4) promote successful training and academic advancement of underrepresented post-doctoral and early career investigators through mentorship, opportunities to participate in community engaged health interventions, and support of pilot projects and subsequent independent cardiometabolic disparities research; 5) conduct rigorous analyses and partner with community stakeholders to identify community, health system, family, and individual-level correlates of health disparities to inform research methods, health policy, and the design of community and health system partnered interventions to mitigate cardiometabolic disparities; and 6) contribute to the development, evaluation, and dissemination of valid, reliable, and generalizable tools that can measure and track health outcomes and the social, behavioral, and economic predictors relevant to multiethnic communities at risk for cardiometabolic disease.

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Original award $3,485,481 $3,485,481
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Subawards

Subrecipient Amount Awarded
Lundquist Institute For Biomedical Innovation At Harbor-Ucla Medical Center Background: The Latinx community has a high burden of chronic kidney disease and worse outcomes than non-Hispanic White patients, due in part to cultural and… $65,400
South Central Prevention 1. Ms. Wright will work with the Center MPI to direct all Center activities and will sit on the Executive Committee. She will work closely with Drs. Brown,… $71,498
Charles R. Drew University Of Medicine And Science Aims: Aim 1: To examine the association between BP control and multi-level factors (patient, provider, clinic, and neighborhood characteristics) before the… $71,000
Lundquist Institute For Biomedical Innovation At Harbor-Ucla Medical Center Objective: This formative study will identify evidence-practice gaps related to LDA prescribing among providers in a retrospective cohort of prenatal patients… $80,000
Olive View / Ucla Education And Research Institute, Inc. ERI will serve as an enrollment site for the project “Blood Pressure Disparities Reduction, Equity, and Access among safety net patients with Cardiovascular… $47,123
Olive View / Ucla Education And Research Institute, Inc. Under the direction of the Principal Investigator, the Project Director hired through the Olive View-UCLA Medical Center (OVMC) Education and Research Institute… $57,634
University Of Southern California The team will design a multilevel, culturally and linguistically tailored, complex intervention for reducing BP among multi-racial, multi-ethnic individuals… $2,395,787
University Of Southern California Identify, support and implement two community health workers or health coaches for the Project 1 intervention and to serve as a resource for the UC END… $535,113
Rancho Research Institute The Rancho site investigators and research staff will recruit 250 individuals with stroke or MI into the BP REACH trial over the course of the 5-year study… $303,787
Lundquist Institute For Biomedical Innovation At Harbor-Ucla Medical Center We will test the impact of this multilevel, culturally and linguistically tailored, complex intervention on SBP for individuals with a history of stroke or MI… $110,981
Cedars-Sinai Medical Center UC END DISPARITIES advances health equity via a multilevel community-academic partnered approach to improve cardiometabolic related health outcomes in… $165,687
The Ohio State University Objective: To lead data analysis for Skills-based Educational strategies for Reduction of Vascular Events in Orange County (SERVE OC)Dr. Jeffrey Wing will lead,… $119,212
University Of Southern California The team will design a multilevel, culturally and linguistically tailored, complex intervention for reducing BP among multi-racial, multi-ethnic individuals… $2,395,787
Olive View / Ucla Education And Research Institute, Inc. ERI will serve as an enrollment site for the project “Blood Pressure Disparities Reduction, Equity, and Access among safety net patients with Cardiovascular… $93,253
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Quick answers

Who received award P50MD017366?

P50MD017366 was awarded to University Of California, LOS Angeles by National Institute for Minority Health and Health Disparities (National Institutes of Health) on September 24, 2021.

How much is award P50MD017366 worth?

$55,295,048 has been obligated on P50MD017366: $51,809,567 in federal funding and $3,485,481 in non-federal funding.

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