Project Grant P425T220046

The National Eye Institute (NEI) awarded a $580,331 Project Grant (CFDA 93.867 - Vision Research) to The Trustees of the Stevens Institute of Technology in Hoboken, New Jersey. This 4-year grant, effective September 1, 2024, aims to develop a deep learning-based diagnostic tool for detecting retinopathy of prematurity (ROP), a leading cause of childhood blindness globally. The key products and services to be delivered under this award include: Optimizing and testing an animal-to-human (A2H)...

The federal Project Grant award R21EY035830 from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) provides $222,208 to The New England College of Optometry to investigate methods for measuring the refractive index of the human eye's crystalline lens. The goal is to develop a novel, non-contact system that can simultaneously measure the refractive index and axial length of the eye, which will improve the accuracy of axial length measurements used in vision research...

The National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), awarded a Project Grant totaling $245,243 to Duke University. This 2-year grant, effective March 1, 2025, aims to develop and validate a novel technique for measuring ocular pulse amplitude (OPA) using fixed-force applanation on normotensive and hypertensive eyes. The research will involve validating the OPA measurement algorithm on non-human primates implanted with an intraocular pressure (IOP)...

The National Eye Institute (NEI) awarded a $256,296 Project Grant (CFDA 93.867 - Vision Research) to The General Hospital Corporation (doing business as Massachusetts General Hospital) to develop a new adaptive ranging optical coherence tomography angiography (OCTA) technology. The project aims to expand the imaging depth range of OCTA, which is used to diagnose and monitor eye diseases affecting the retinal microvasculature, such as diabetic retinopathy and macular degeneration. The project...

The Salus University received a $371,158 project grant award from the Department of Education's Office of Postsecondary Education under the Education Stabilization Fund federal grant program. The one-year grant period runs from July 13, 2022 to July 12, 2023. Under this award, Salus University's Eye Institute will deliver services to respond to the COVID-19 pandemic. As the CFDA program description indicates, funding through the Education Stabilization Fund aims to prevent, prepare for, and...

The National Eye Institute (NEI) awarded a $853,894 Project Grant under the Vision Research program (CFDA 93.867) to Childrens Hospital Medical Center to investigate the "Mechanisms of Placentally-Mediated ROP Protection". The research aims to characterize how placental factors like the LHX5 transcription factor may contribute to postnatal vascular protection and reduced risk of retinopathy of prematurity (ROP) in preterm infants, a leading cause of childhood blindness. The project...

This $488,639 Project Grant award, issued by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867), aims to identify the mechanisms underlying the enhanced virulence of an extensively drug-resistant (XDR) strain of Pseudomonas aeruginosa causing a recent outbreak of keratitis. The research objectives are to systematically test the virulence factors of this new P. aeruginosa strain and to develop more effective ocular antibiotic formulations for treating...

This Project Grant awarded by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) funds the development and evaluation of novel surrogate augmented deep predictive learning algorithms to predict referral-warranted retinopathy of prematurity (RW-ROP). The primary goals are to: Develop algorithms that leverage early retinal images and demographic factors to accurately predict RW-ROP, enabling earlier identification of high-risk infants for close monitoring and...

This Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) provides $813,213.00 to the Icahn School of Medicine at Mount Sinai to conduct a multi-omic study on the preclinical phase of primary open-angle glaucoma (POAG). The key products and services to be delivered under this award include: Analyzing plasma proteomic and metabolomic markers, as well as their interactions with genetic predisposition, to better understand POAG pathophysiology. This will involve using...

The National Eye Institute (NEI) awarded a $623,090 Project Grant (CFDA 93.867 - Vision Research) to Oregon Health & Science University (OHSU) to develop a wide-field visible-light optical coherence tomography (WF-VIS-OCT) device optimized for the rat eye model of oxygen-induced retinopathy (OIR). The goals are to: 1) Build the new WF-VIS-OCT system capable of high-resolution 5-mm field-of-view imaging; 2) Develop deep learning algorithms to quantify retinal capillary vasculature, blood...