Project Grant P30GM165295
- The National Institute of General Medical Sciences awarded Arkansas Children's Research Institute $107,307 on June 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) for a K99/R00 career development grant studying the mechanisms of muscle catabolism and hypermetabolism following burn injury and burn sepsis. The award funds research into the underlying pathophysiological mechanisms driving muscle wasting, excessive metabolic stress, and impaired wound healing in...
- This $154,000 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports the Arkansas Children's Research Institute's research on the unique DNA methylation landscape of deregulated enhancers in CBFA2T3-GLIS2 positive pediatric acute megakaryoblastic leukemia. The award period runs from November 1, 2024 to October 31, 2026. The research aims to advance the scientific understanding of this rare pediatric cancer subtype and...
- The National Heart, Lung, and Blood Institute awarded the University of Arkansas for Medical Sciences $244,378 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to improve school-parent coordination to prevent nicotine use among rural youth. The award is a Project Grant (R34HL186222) extending through May 31, 2029, performed in Little Rock, Arkansas. The funded work adapts a nicotine-use prevention program for rural settings and identifies...
- The National Institute of Child Health and Human Development awarded the University of South Carolina $1,237,094 on September 15, 2025, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to study the efficacy of center-based childcare in mitigating unhealthy weight gain in preschoolers from low-income households during summer months. The study targets preschool-age children from households at or below 185% poverty level or Medicaid-eligible, a...
- The National Heart, Lung, and Blood Institute awarded the University of Arkansas $546,654 on May 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and validate computational models for predicting and controlling cardiac fibrosis in heart failure patients with reduced ejection fraction. The project integrates systems mechanobiology modeling with experimental cell culture platforms and patient clinical data to identify cardiac fibroblast signaling feedback...
- The National Institutes of Health Office of the Director awarded Arkansas Children's Research Institute $1,451,548 on July 1, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to conduct a national, fully-remote natural-experiment study identifying hormonal and digital biomarkers predictive of smoking cessation outcomes in women of reproductive age. The research addresses the lower efficacy of evidence-based smoking cessation interventions in women compared to men and the...
- The National Institute of Child Health and Human Development awarded The Trustees of Columbia University in the City of New York $167,400 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the relationships between early relational health, maternal unpredictability, and infant adiposity as risk factors for early childhood obesity. The research will determine associations between early relational health constructs (including...
- The National Institute of Child Health and Human Development awarded the University of Pittsburgh $248,858 on July 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to develop and test network interventions that increase adoption of evidence-based obesity prevention strategies among community coalitions serving low-income populations. The research addresses the 23–33 percent higher obesity prevalence among children from socioeconomically...
- The National Institute of General Medical Sciences awarded Brown University $1.196 million on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support Phase 3 of the Center for Computational Biology of Human Disease (CBHD), a COBRE project. The award funds expansion of the Computational Biology Core (CBC) facility, which provides analysis services for large-scale biological datasets relevant to human disease research. Brown will solidify the research...
- The National Institutes of Health's National Heart, Lung and Blood Institute awarded $2,350,623 under the Cardiovascular Diseases Research program (CFDA 93.837) to the Regents of the University of Minnesota on May 1, 2021 for a project concluding on April 30, 2022. The project aims to reduce childhood obesity through an individual randomized controlled trial testing combinations of ecological momentary intervention, home visiting, and video feedback delivered to 510 low-income, racially...
The National Institute of General Medical Sciences awarded Arkansas Children's Research Institute $1,167,290 on August 1, 2026, to establish and operate the Center for Childhood Obesity Prevention at the Arkansas Children's Research Institute under the Biomedical Research and Research Training program (CFDA 93.859). The center addresses pediatric obesity and cardiometabolic disorders in Arkansas and nationally by integrating biomedical discovery, clinical translation, and community engagement. Phase 3 activities include strengthening and expanding three research cores—biostatistics, metabolism and bioenergetics, and community engagement—to accelerate discovery and cross-disciplinary integration; advancing investigator career development through structured mentoring, pilot funding, and training programs that foster team science; and implementing a comprehensive sustainability plan anchored by institutional commitments, fee-for-service cost-recovery models, and diversified extramural funding to secure the center's long-term independence. The center builds on prior COBRE phases that established high-performing research cores and supported investigators who published over 530 peer-reviewed manuscripts. Work is performed in Little Rock, Arkansas, with a period of performance through April 30, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 7/24/26 |