Project Grant P30GM154633
- Grant Award Summary The Children's Hospital of Philadelphia Research Institute received a $1.52M Cooperative Agreement from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 24, 2025, with completion scheduled for July 31, 2030. This award funds the Pediatric Fungal Network Study of Rare Invasive Fungal Diseases in Immunocompromised Pediatric Patients (PFN-STRIDE) Rare...
- Federal Grant Award Summary Cincinnati Children's Hospital Medical Center received a $866,250 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) on September 9, 2025. The award supports a two-year research initiative through August 31, 2027, focused on developing predictive approaches to mitigate drug-induced liver injury (DILI) risk in pediatric populations. The...
- Federal Grant Award Summary The National Cancer Institute awarded Seattle Children's Hospital (doing business as Seattle Children's Research Institute) a $3.48 million Project Grant under the Cancer Treatment Research program (CFDA 93.395) effective August 1, 2025, through July 31, 2029. This project systematically identifies genomic heterogeneity and relapse predictors in pediatric and adolescent/young adult patients with Philadelphia chromosome-positive (PH+) and ABL-class PH-like acute...
- Grant Award Summary Cincinnati Children's Hospital Medical Center received a $803,854 Project Grant award dated June 1, 2025, from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award supports research through March 31, 2030, investigating the functions of long terminal repeat (LTR) retrotransposon activation during preimplantation embryonic development. The project aims to determine...
- Federal Grant Award Summary Children's Mercy Hospital received a $1,385,834 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 15, 2025 through July 31, 2030. The project investigates state-level variability in pediatric hospitalizations and reported child maltreatment among low-socioeconomic status (SES) families, hypothesizing that state...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Arkansas Children's Research Institute a $1.39 million Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) effective July 1, 2025, through May 31, 2030. The award funds the ELECTRA Pregnancy Study, which evaluates maternal and neonatal pharmacokinetics of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulators...
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a $474,878 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded August 1, 2025, with a completion date of July 31, 2027. The research project, "Quantifying the Impact of Hyperglycemia on Embryonic Metabolism and Development in C. elegans," generates single-cell...
- Summary: University of Michigan Pediatric Pulmonary Center The University of Michigan received a $680,000 Project Grant from the Maternal and Child Health Bureau (MCHB) under the Special Projects of Regional and National Significance (SPRANS) program (CFDA 93.110), effective July 1, 2025 through June 30, 2030. The award supports the establishment of the University of Michigan Pediatric Pulmonary Center (UMPPC), which will develop an interprofessional training infrastructure for healthcare...
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a $120,375 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective April 15, 2026, with completion anticipated by January 31, 2028. The award supports the development of FLUME (Fetal Lung Multiomics Exploration), a human fetal lung multiomics cell atlas with computational models designed to predict fetal...
- Federal Cooperative Agreement Summary Seattle Children's Hospital, doing business as Seattle Children's Research Institute, received a $4.6 million Cooperative Agreement from the National Institute of Neurological Disorders and Stroke under the Drug Use and Addiction Research Programs (CFDA 93.279) on September 19, 2025, with completion targeted for July 31, 2030. This award funds the development of a precision health model for pediatric chronic primary pain that leverages the PEDSnet national...
CENTER FOR PEDIATRIC RESEARCH - OVERALL PROJECT SUMMARY THE PRIMARY GOAL OF THIS APPLICATION IS TO CONTINUE TO HARNESS THE CAPABILITIES OF THE CENTER FOR PEDIATRIC RESEARCH TO SUPPORT BASIC AND TRANSLATIONAL SCIENTISTS STUDYING MECHANISMS UNDERLYING CHILDREN'S DISEASE AND ASSOCIATED TREATMENT OPTIONS. THE ORIGIN OF MANY PEDIATRIC DISEASES IS FROM ALTERED DEVELOPMENTAL PROGRAMMING RELATED TO THE PROCESSES OF CELL PROLIFERATION, MORPHOGENESIS, MIGRATION, DIFFERENTIATION, AND PROGRAMMED DEATH. THESE DEVELOPMENTAL PROCESSES ARE AT THE ROOT OF PEDIATRIC DISEASE AND ARE DISRUPTED THROUGH GENETIC DISORDERS, ABERRANT FETAL PROGRAMMING, ALTERED GROWTH & DEVELOPMENT, AND ENVIRONMENTAL PRESSURES. OUR MULTIDISCIPLINARY CENTER APPLIES GENETIC, BIOCHEMICAL, CELL, AND MOLECULAR APPROACHES ACROSS SEVERAL MODEL ORGANISMS TO CHARACTERIZE ALTERATIONS DURING DEVELOPMENT AS THEY PERTAIN TO PEDIATRIC DISEASES AND DISORDERS. FOR PHASE III WE WILL CONTINUE TO BUILD UPON THE SUCCESS OF PHASE I AND II EFFORTS IN CREATING A CRITICAL MASS OF INDEPENDENTLY FUNDED INVESTIGATORS WITHIN THE CENTER FOR PEDIATRIC RESEARCH BY REFINING OUR FOCUS TO SUPPORT AND MENTOR BOTH NEW AND ESTABLISHED INVESTIGATORS. CENTER SUCCESS WILL BE ACHIEVED THROUGH THE FOLLOWING AIMS: 1) MAINTAIN A SUPPORTIVE ENVIRONMENT FOR THE TRAINING AND MENTORSHIP OF SCIENTISTS STUDYING PEDIATRIC DISEASE TO STRENGTHEN AND GROW THE CENTER MEMBERSHIP; 2) UTILIZE AND ENHANCE EXISTING CORE RESOURCES THAT SUPPORT PEDIATRIC RESEARCH WITH A FOCUS ON LONG-TERM SUSTAINABILITY; 3) EXPAND TRAINING AND LEARNING OPPORTUNITIES RELEVANT TO PEDIATRIC DISEASE; AND 4) EVALUATE SUCCESS OF THE CENTER. THROUGH THESE AIMS, THE CENTER FOR PEDIATRIC RESEARCH WILL DEVELOP A STRONG FOUNDATION IN BASIC AND TRANSLATIONAL RESEARCH BY FOSTERING A COLLABORATIVE ENVIRONMENT FOR SCIENTISTS AND PHYSICIANS. STRENGTHENED BY OUR INSTITUTION'S STRONG COMMITMENT TO CHILDREN'S MEDICINE, PHASE III FUNDING WILL BE INSTRUMENTAL IN ENHANCING PEDIATRIC RESEARCH EFFORTS IN THE CENTER, THE REGION, AND BEYOND.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 7/16/25 | ||
| Not listed | $0 | 9/10/24 | ||
| Not listed | $1.3m | 6/18/24 | ||
| Not listed | $1.3m | 6/18/24 |
GrantNumber | Description | Subgrantee | Prime Award | Dollars Obligated | Updated At |
|---|---|---|---|---|---|
CY23116SDSUS | South Dakota State University | Project Grant P30GM154633 | $41.3k | 9/16/25 | |
CY23116USDS | The University Of South Dakota | Project Grant P30GM154633 | $50.0k | 12/27/24 |