This federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) provides $2,173,794 to The General Hospital Corporation (Massachusetts General Hospital) to conduct research on enhancing brain resilience to Alzheimer's disease by targeting adult hippocampal neurogenesis. The project aims to explore the mechanisms by which adult hippocampal neurogenesis cooperates with brain-derived neurotrophic factor (BDNF) to potentially slow cognitive decline in...
The National Institute on Aging (NIA) awarded a $2,501,096 Project Grant (CFDA 93.866 - Aging Research) to the Regents of the University of Minnesota's Office of Sponsored Projects Administration on August 15, 2024. This grant, titled "Establishing Mechanisms of Benefit to Reinforce the Alzheimer's Care Experience AD/ADRD Roybal Center: EMBRACE", aims to provide scientific infrastructure to support the testing of mechanisms in tailored home and community dementia care intervention...
This $1,177,500 federal Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) supports the Arizona State University (ASU) Roybal Center for Older Adults Living Alone with Cognitive Decline. The center will develop and conduct clinical trials of technology-enabled behavioral and lifestyle interventions to delay Alzheimer's disease and related dementias (ADRD) and improve quality of life in older adults living alone with cognitive decline,...
The National Institute on Aging (NIA) awarded a $459,250 Project Grant (CFDA 93.866 - Aging Research) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to investigate and validate the use of dried blood spot (DBS) samples for measuring Alzheimer's disease (AD) biomarkers. The key objectives are to: 1) optimize fingerstick collection methods and validate assays for three key AD biomarkers (pTau217, GFAP, and NFL) in DBS samples; 2) establish if DBS...
The National Institute on Aging (NIA), part of the Department of Health and Human Services National Institutes of Health, awarded a $3.37 million Project Grant to The University of Texas at Arlington to develop an individualized deep connectome framework for Alzheimer's disease and related dementias (ADRD) analysis. The three-year grant, awarded on August 18, 2022 under the NIA's Aging Research program (CFDA 93.866), will support research to discover and identify individualized...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $459,250 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to conduct a longitudinal study investigating the impact of stress and resilience on Alzheimer's disease-related brain pathology and cognitive function. The research aims to elucidate the sequential relationships between stress, resilience, and the development of Alzheimer's disease over time,...
The federal Project Grant award of $5,262,301 from the National Institute on Aging (NIA) under the Aging Research (CFDA 93.866) program supports the "Triangulation of Innovative Methods to END AD (TIME-AD)" project. The project aims to strengthen causal inference in observational data to better understand Alzheimer's disease (AD) and Alzheimer's disease related dementias (ADRD) risk factors. The project includes four research projects that will use innovative methods like doubly robust...
This federal Cooperative Agreement award of $2,929,176.00 from the National Institute on Aging's Aging Research program (CFDA 93.866) establishes a Coordinating Center for economic research on Alzheimer's disease (AD) and AD-related dementia (ADRD) at the National Bureau of Economic Research (NBER). The Center will encompass 4-5 research projects from a companion program, as well as NBER's ongoing ADRD research and new projects selected annually. Key focus areas include caregiving, ADRD...
This $2,497,615 federal Project Grant award, funded by the National Institute on Aging under the Aging Research program (CFDA 93.866), aims to evaluate the impact of new Medicare home health agency (HHA) payment policies on healthcare utilization and outcomes for Medicare beneficiaries with Alzheimer's disease and related dementias (ADRD). The project has three key objectives: 1) characterizing changes in the ADRD beneficiary population eligible for HHA services, 2) evaluating the effect of...
This Project Grant award, titled "Care for Persons with Dementia in Medicare Advantage and Traditional Medicare: Family Spillovers and Disparities", is funded by the National Institute on Aging (CFDA 93.866 - Aging Research) for $2,462,393 with a project period from August 15, 2024 to April 30, 2029. The grant aims to study healthcare utilization and intergenerational transfers among Medicare beneficiaries with Alzheimer's disease and related dementias (ADRD), comparing experiences...
The National Institute on Aging (NIA) awarded a $3,572,166 Project Grant (CFDA 93.866 - Aging Research) to the Massachusetts General Hospital (MGH) to establish the "Massachusetts General Hospital Roybal Center for Behavioral Dyadic Research in Alzheimer's Disease and Related Dementias (CONFIDE-ADRD)". The project aims to develop, optimize, test, and implement dyadic behavioral prevention interventions (DBPIs) across the spectrum of Alzheimer's disease and related dementias (ADRD) in both hospital and community settings. The grant will support the center's two cores: the Administrative Core, which will coordinate activities and provide experiential learning opportunities, and the Behavioral Intervention Development Core, which will assist awardees in conducting feasible, rigorous, and mechanistic DBPI pilot research. The project will also involve sub-awards to the Benjamin Rose Institute and the University of Washington to adapt cultural interventions and conduct technical research, respectively. The project period runs from August 2024 to May 2026.