Project Grant P20GM125526

Grant Award Summary The National Institute on Aging (NIA) awarded $770,644 to the University of Texas Health Science Center at San Antonio on September 1, 2025, under the Aging Research program (CFDA 93.866) to establish the Center for Alzheimer's Disease and Related Dementias (AD/ADRD) Population Aging and Social Studies (CAPAS). This two-year project grant operates through three coordinated cores: an Administrative Core providing scientific and administrative leadership, networking, and...

Federal Grant Award Summary The National Institute on Aging awarded Cedars-Sinai Medical Center $1.466 million under the Aging Research program (CFDA 93.866) for the Los Angeles Claude D. Pepper Older Americans Independence Center (LA OAIC), a collaborative initiative with UCLA and USC. The award, effective September 1, 2025 through August 31, 2030, supports the establishment of an integrated research center designed to accelerate translational geroscience and extend human healthspan. The LA...

Federal Project Grant Summary The National Institute on Aging awarded University of California, Irvine $6.26 million through the Aging Research program (CFDA 93.866) for the Discovery and Trial Ready Cohort for Limbic Predominant Age Related TDP-43 Encephalopathy (TRC LATE) project, effective September 1, 2025, through June 30, 2030. This project addresses critical gaps in understanding LATE-neuropathologic change (LATE-NC), a common pathological condition affecting cognitive decline in older...

Federal Cooperative Agreement Summary The National Center for Advancing Translational Sciences (National Institute on Aging, Aging Research program, CFDA 93.866) awarded a cooperative agreement totaling $1,392,133 to Cedars-Sinai Medical Center, effective August 15, 2025, through July 31, 2030. This research initiative develops microphysiological systems (MPS), also known as organ-on-chips, utilizing human induced pluripotent stem cells (hiPSCs) to model inflammaging and spaceflight-induced...

Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Scripps Research Institute a Project Grant of $645,242 under the Aging Research program (CFDA 93.866), effective July 1, 2026, through March 31, 2031. The award supports research on chemical modulation of proteostasis to promote longevity and healthy aging. The project focuses on developing chemical and computational tools to selectively attenuate polysome-mediated translation in aging neurons while preserving...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $430,603 to the University of Toledo's Health Science Campus Division to investigate the mechanisms by which age-associated transfer RNA (tRNA) modification aberrations affect tRNA cleavage and contribute to cellular senescence. The key research objectives are to examine tRNA and tRNA-derived fragment modification levels in tissues that commonly manifest age-related dysfunction, as well as...

Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Boston University Medical Campus a $3.35 million project grant on September 15, 2025, under the Aging Research program (CFDA 93.866) to investigate transfer ribonucleic acid (tRNA) epitranscriptome dysregulation and translational dysfunction in Alzheimer's Disease and Related Disorders (ADRD). The project, extending through May 31, 2030, will examine how modifications to the approximately 250 different tRNAs in...

Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of Maryland, College Park $456,064 on September 1, 2025, to support the Southern Population Aging Research Center (SPARC), a multi-institutional research center co-led by the University of Maryland College Park, University of Alabama at Birmingham (UAB), and University of Maryland Baltimore County (UMBC). Under the Aging Research program (CFDA 93.866), SPARC fosters interdisciplinary collaboration to advance...

Project Grant Summary: Center for Seniors Uniting Nationwide to Support Health, Integrated Care, and Economics (SUNSHINE) The National Institute on Aging (NIA) awarded a $463,318 Project Grant to the University of Maryland, College Park to establish and operate the SUNSHINE Center, an interdisciplinary research initiative focused on advancing aging resilience through integrated healthcare systems, public health organizations, and community-based resources. Funded under the Aging Research program...

Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded $745,808 to the University of Texas Health Science Center at San Antonio under the Aging Research program (CFDA 93.866) on September 20, 2025, for an R25 educational grant extending through May 31, 2030. This initiative delivers annual advanced hands-on clinical research training courses focused on Down Syndrome (DS) clinical research across the lifespan, recruiting and training 16 post-graduate participants...