Biology and structure of pmhc receptors functioning as mechanosensors in the [alpha][beta] t-cell lineage

Active Project Grant Awarded Last action

Award ID
P01AI143565
Recipient
Awarding agency
Obligated
$37,575,631

Award facts

Assistance listing
93.855 Allergy and Infectious Diseases Research
Completion date 62% complete
Originally
Funding
  • $32,728,103.00 Federal
  • $4,847,528.00 Non-federal
Place of performance
Boston, MA 02215, USA

Award details come from USAspending.gov.

Transactions

Action Federal Non-federal Date
Amendment $2,515,488 $0
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Amendment $2,422,263 $0
Amendment $2,422,263 $2,422,263
Amendment $2,425,265 $0
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Original award $2,444,290 $0
Show all 18

Subawards

Subrecipient Amount Awarded
Texas A&M Engineering Experiment Station Dr. Hwang at Texas A&M is the PI of Core C (Molecular Dynamics) in the P01 project. He will design and carry out simulations of T-cell receptor (TCR) and its… $179,291
Vanderbilt University The Lang Lab will perform optical tweezers experiments to directly investigate the mechanobiology of TCR-pMHC bonds and T cell triggering using our single… $167,659
Vanderbilt University The Lang Lab will employ optical tweezers-based methods to measure the TCR-pMHC bonds and T cell triggering using single molecule and single cell methods.… $211,944
Texas A&M Engineering Experiment Station Dr. Hwang at Texas A&M is the PI of Core C (Molecular Dynamics) in the P01 project. He will design and carry out simulations of T-cell receptor (TCR) and its… $131,037
Vanderbilt University The Lang Lab will employ optical tweezers based methods to measure the TCR-pMHC bonds and T cell triggering using single molecule and single cell methods.… $226,922
Vanderbilt University $171,226
President And Fellows Of Harvard College NMR methods will be developed to aid the resonance assignment, structure determination and the analysis of dynamics and conformational exchange in preTCR, TCR… $199,410
Vanderbilt University The Lang Lab will employ optical tweezers based methods to measure the TCR-pMHC bonds and T cell triggering using single molecule and single cell methods.… $226,914
Vanderbilt University $171,228
President And Fellows Of Harvard College NMR methods will be developed to aid the resonance assignment, structure determination and the analysis of dynamics and conformational exchange in preTCR, TCR… $199,410

Quick answers

Who received award P01AI143565?

P01AI143565 was awarded to Dana-Farber Cancer Institute, Inc. by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on July 29, 2020.

How much is award P01AI143565 worth?

$37,575,631 has been obligated on P01AI143565: $32,728,103 in federal funding and $4,847,528 in non-federal funding.

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