Project Grant NU58DP007057
- The National Heart, Lung, and Blood Institute (NHLBI) awarded Yale University a $764,853 Project Grant on August 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct the CALM-OSA study through May 31, 2030. This research initiative will investigate the role of arousal threshold (ARTH)—an individual's propensity to awaken from respiratory stimuli—as a key determinant of treatment adherence and clinical outcomes in obstructive sleep apnea (OSA) patients receiving...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Northern California Institute For Research And Education, Inc. (NCIRE) a $1,270,508 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to improve the identification and diagnosis of obstructive sleep apnea (OSA) in women. The award, obligated on September 20, 2025, with completion targeted for August 31, 2027, addresses a critical gap in OSA screening and diagnosis. The...
- Federal Grant Award Summary Award Details: The National Heart, Lung, and Blood Institute (NHLBI) awarded Brigham and Women's Hospital a $818,279 Project Grant effective September 1, 2025, through May 31, 2029, under the Cardiovascular Diseases Research program (CFDA 93.837). The project, titled "Leveraging Research and Clinical Cohorts to Improve Obstructive Sleep Apnea Subtyping," addresses critical gaps in obstructive sleep apnea (OSA) diagnosis and treatment prediction by developing...
- Federal Grant Award Summary The University of Pennsylvania received a $782,473 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), with an award date of September 15, 2025, and completion target of July 31, 2029. This research project aims to improve understanding of obstructive sleep apnea (OSA) pathogenesis through the application of novel imaging techniques during sleep. The research will combine...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded Icahn School of Medicine at Mount Sinai a Project Grant of $464,750 under the Aging Research program (CFDA 93.866) to conduct biomedical research examining the mechanisms by which obstructive sleep apnea (OSA) contributes to Alzheimer's disease pathology. The research specifically differentiates the separate contributions of chronic sleep disruption and intermittent hypoxia on tau protein propagation and neurofibrillary...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded The University of Texas Health Science Center at San Antonio $449,861 under the Oral Diseases and Disorders Research program (CFDA 93.121) to conduct a 24-month clinical observational feasibility study examining dental practitioners' oral appliance therapy (OAT) titration methods for obstructive sleep apnea (OSA) and their associated patient outcomes. Initiated on June 17, 2025, the...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of California, Irvine a Project Grant totaling $1,296,660 under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct an integrated "bed to bench" research initiative investigating the mechanistic pathways linking obstructive sleep apnea (OSA) to cardiovascular disease (CVD). The award, issued on September 25, 2025, with an ultimate completion date of June 30,...
- The Department of Defense, through the Military Medical Research and Development program (CFDA 12.420), awarded a $5,465,906 Project Grant to the University of Maryland, Baltimore to conduct the "TELE-SLEEP OSA" study. This 4-year research project aims to evaluate the clinical effectiveness, implementation, and economic impact of telehealth care for obstructive sleep apnea within the Military Health System. The University of Maryland, Baltimore has issued a $1,892,006 sub-grant to...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded University of California, Irvine a Project Grant of $128,097 under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate the cardiac effects of obstructive sleep apnea (OSA). The research addresses a critical gap in understanding why continuous positive airway pressure (CPAP) treatment fails to eliminate cardiovascular disease (CVD) risk in all OSA patients. The project will deliver...
- Federal Project Grant Award Summary Berendo Scientific LLC received a $583,718 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 15, 2025, with completion targeted for August 30, 2026. The award funds development and evaluation of SLEEPFLEX, a non-invasive head and neck exercise program designed to treat mild to moderate obstructive sleep apnea (OSA). The deliverables include optimization...
OBSTRUCTIVE SLEEP APNEA (OSA) AWARENESS PROJECT - PURPOSE? THE PURPOSE OF THE OBSTRUCTIVE SLEEP APNEA (OSA) AWARENESS PROGRAM IS TO REDUCE THE NUMBER OF INDIVIDUALS LIVING WITH UNDIAGNOSED AND/OR UNTREATED OSA THROUGH A COMPREHENSIVE AWARENESS PROGRAM FOCUSED TOWARD EDUCATING THE?GENERAL?PUBLIC,?PUBLIC HEALTH?ORGANIZATIONS?AND?HEALTH CARE PROVIDERS.?THIS PROGRAM WILL?PROMOTE?AWARENESS OF OSA AS WELL AS TESTING PROCEDURES, DIAGNOSIS AND REFERRAL OPTIONS, AND TREATMENT AND LONG-TERM MANAGEMENT OPTIONS, WHICH WILL RESULT IN INCREASED HEALTH CARE PROVIDER AND PUBLIC RECOGNITION OF THE DISORDER, INCLUDING INCREASED SCREENING FOR OSA BY PRIMARY CARE AND PUBLIC HEALTH PROVIDERS WHO ARE THE FIRST POINT OF HEALTH CARE CONTACT FOR MANY PATIENTS. INCREASING AWARENESS OF PUBLIC HEALTH DATA RELATED TO OSA WILL SPUR PUBLIC HEALTH STAKEHOLDERS TO ADDRESS THIS ISSUE WITH POPULATIONS AFFECTED BY THIS DISORDER.?THIS WILL SUPPORT THE SLEEP HEALTH GOALS OF HEALTHY PEOPLE 2030 BY ?INCREASING THE PROPORTION OF ADULTS WITH SLEEP APNEA SYMPTOMS WHO GET EVALUATED BY A HEALTH CARE PROVIDER.??THE DRIVING FORCE BEHIND THE PROGRAM WILL BE THE FORMATION OF A COALITION OF PARTNERS AND COLLABORATORS THAT WILL WORK TOGETHER IN AN ACTIVE ALLIANCE TO MAKE A SIGNIFICANT, WIDESPREAD AND MEASURABLE IMPACT ON PUBLIC AND PROFESSIONAL AWARENESS OF OSA THAT ULTIMATELY RESULTS IN POSITIVE BEHAVIOR CHANGE. OUTCOMES? OUTCOME 1: INCREASED AWARENESS OF OSA PUBLIC HEALTH DATA AMONG PUBLIC HEALTH PROFESSIONALS AND NON-SLEEP HEALTH PROFESSIONALS? OUTCOME 2: INCREASED DEVELOPMENT AND DISSEMINATION OF EVIDENCE-BASED PUBLIC HEALTH STRATEGIES TO ADDRESS?OSA? OUTCOME 3: INCREASED AWARENESS OF OSA, TESTING OPTIONS, REFERRAL OPTIONS, AND TREATMENT/MANAGEMENT OPTIONS AMONG PUBLIC HEALTH PROFESSIONALS AND NON-SLEEP HEALTH PROFESSIONALS? OUTCOME 4: INCREASED AWARENESS OF OSA, TESTING PROCEDURES, AND EVIDENCE-BASED TREATMENT/MANAGEMENT OPTIONS IN THE GENERAL PUBLIC,?INCLUDING SPECIFIC POPULATIONS AFFECTED BY HEALTH DISPARITIES IN RELATION TO?OSA? OUTCOM E 5: INCREASED USE OF SLEEP APNEA SCREENING TOOLS/QUESTIONS?BY NON-SLEEP HEALTH PROFESSIONALS?
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($13k) | 3/9/25 | ||
| Not listed | $0 | 12/20/23 | ||
| Not listed | $0 | 12/20/23 | ||
| Not listed | $0 | 12/20/23 | ||
| Not listed | $377.2k | 6/30/23 |