Project Grant K43TW012887

Award Date 9/1/24
Completion Date 8/31/29
Dollars Obligated $113K
Federal Grant Program
93.989
Assistance Type
Project Grant
Place of Performance
South Africa
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  1. Assess differences in urine metabolite profiles during early pregnancy between women living with and without HIV
  2. Develop risk prediction models for gestational weight gain, postpartum weight retention, and postpartum adiposity using metabolite and clinical data
  3. Elucidate the metabolic pathways associated with the identified predictive metabolites

The project will provide preliminary data to support a future large-scale study examining biomarker profiles for metabolically healthy versus unhealthy weight outcomes in this population. The research aims to inform the development of a urinary metabolite-based screening tool to minimize metabolic comorbidities in pregnant and postpartum women living with HIV.

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