Adapting an evidence-based intervention to improve HIV testing and prep uptake among young men who have SEX with men in vietnam

Ended Project Grant Awarded Last action

Award ID
K43TW012850
Recipient
Awarding agency
Obligated
$468,093

Award facts

Completion date
Place of performance
Vietnam

Award details come from USAspending.gov.

Description

Abstract
Young men who have SEX with men (YMSM) are experiencing an ongoing HIV epidemic in vietnam, with an HIV prevalence of 12%. However, HIV testing and pre-exposure prophylaxis (PREP) use among YMSM remain low. To improve HIV testing and PREP use, mobile health (MHEALTH) interventions hold great promise to reach YMSM in low- and middle-income countries (LMIC). Healthmindr, an evidence-based MHEALTH intervention developed in the united states for men who have SEX with men, is an ideal option for adaptation for YMSM in vietnam. I propose to adapt this APP and explore barriers and facilitators of implementing the APP among YMSM in vietnam. The specific aims are to (1) adapt the healthmindr APP to improve HIV testing and PREP uptake among YMSM in vietnam; (2) examine acceptability, feasibility and preliminary effectiveness of the adapted APP among YMSM in vietnam and (3) explore barriers and facilitators of implementing the adapted APP among YMSM in vietnam. In aim 1, theater testing will be conducted through focus group discussions with YMSM and key other stakeholders, including health officials, clinic staff and community-based organizations. Theater testing data will be used to refine the APP for beta testing. During beta testing, a small group of YMSM will use the APP for 30 days, then complete an online survey and an exit interview to rate the APP's usability, provide their perspectives of the APP and report any other areas for improvement. APP analytics will also be collected to understand whether and how the APP is used. In aim 2, the adapted APP with be tested among YMSM through a randomized controlled design. YMSM will be randomized into the intervention or control arm (1:1 ratio). The intervention arm will have full access to the APP for 3 months, while the control group will receive standard-of-care HIV services. Key APP features include HIV test planning, risk and PREP eligibility assessment, ordering of free condoms and HIV test kits, information about PREP, and PREP provider and HIV testing locations. HIV testing and PREP use will be assessed at baseline and 3 months and compared between groups. A mixed methods approach will be used to evaluate APP acceptability and feasibility. Quantitative data on acceptability and feasibility will be collected through the 3-month online survey, while qualitative data will be collected through in-depth interviews with a subset of YMSM in the intervention arm and other key stakeholders. In aim 3, through the same qualitative study as aim 2, factors that influence the implementation of the APP will be explored. Determinants from seven domains will be identified: condition, technology, value proposition, adopter system, health organization, wider system and embedding/adaption over time. Only when MHEALTH interventions are both effective and adopted can they maximize their potential to reduce HIV incidence among target populations. This proposal will generate data for designing a full-scale hybrid type 1 effectiveness-implementation trial to test the adapted APP and identify implementation strategies to address the barriers of APP implementation in lmics.

Transactions

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Original award $66,427
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Quick answers

Who received award K43TW012850?

K43TW012850 was awarded to Hanoi Medical University by Fogarty International Center (National Institutes of Health) on September 1, 2024.

How much is award K43TW012850 worth?

$468,093 has been obligated on K43TW012850.

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