Project Grant K23HL181400
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded $801,261 to Arkansas Children's Research Institute on May 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to support research on Partial Heart Transplantation (PHT) transplant biology. The project, scheduled for completion by February 28, 2031, aims to advance clinical protocols for pediatric patients by investigating clinically relevant aspects of PHT that distinguish it...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Children's Hospital of Philadelphia a $180,174 Project Grant effective August 1, 2025, through July 31, 2030, under the Cardiovascular Diseases Research program (CFDA 93.837). This award supports the development of an improved framework for designing next-generation pediatric acute respiratory distress syndrome (ARDS) clinical trials. The research addresses limitations in current trial methodologies...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded $234,000 to the University of Colorado-Denver under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct a prospective study examining the relationship between directly measured skin pigmentation and pulse oximetry bias. The two-year project (September 1, 2025 – August 31, 2027) addresses a critical gap in medical device validation by objectively measuring skin pigmentation to assess its...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Children's Hospital of Philadelphia Research Institute a $594,583 Project Grant effective August 10, 2025, through May 31, 2029, under the Cardiovascular Diseases Research program (CFDA 93.837). This research project, titled "Origins of Neonatal Lung Myofibroblasts," focuses on advancing understanding of myofibroblast development and function during neonatal lung maturation. The research...
- Federal Project Grant Award Summary The University of Arkansas, Fayetteville received a $546,654 Project Grant from the National Heart, Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded May 1, 2026, with completion targeted for January 31, 2030. The grant funds research into cardiac fibroblast modeling to predict and control fibrosis in heart failure patients with reduced ejection fraction (HFrEF). The research integrates computational...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Oregon Health & Science University a $737,378 Project Grant on June 5, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct a follow-up study of preterm infants participating in a randomized controlled trial evaluating extended Continuous Positive Airway Pressure (ECPAP) therapy. The research will continue longitudinal evaluation of former preterm infants through school...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Children's Hospital of Philadelphia Research Institute a $182,234 Project Grant effective July 16, 2025, through April 30, 2027, under the Cardiovascular Diseases Research program (CFDA 93.837). Under the principal direction of Dr. Jelte Kelchtermans, the project delivers research services focused on identifying and predicting pediatric asthma exacerbations triggered by ambient air pollution (AAP)...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of North Carolina at Chapel Hill a Project Grant of $639,474 under the Cardiovascular Diseases Research program (CFDA 93.837) on September 15, 2025, with a completion date of June 30, 2029. This award funds an expansion of the BACHPAN birth cohort study in rural Pakistan to investigate the relationship between childhood adversity—including prenatal and early childhood exposure to poverty,...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Columbia University's Health Sciences Division a Project Grant of $868,048 on May 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837). This research initiative, titled "Predictors of Airway Dysanapsis in Early Life (PADEL)," will be conducted through February 28, 2031, at the institution's New York location. The grant funds a longitudinal research study examining the...
- Federal Project Grant Award Summary Funding Agency & Program: National Heart, Lung, and Blood Institute (NHLBI), Cardiovascular Diseases Research Program (CFDA 93.837) Award Details: Trustees of Tufts College received a $134,537 Project Grant awarded September 5, 2025, with a completion date of June 30, 2030, to develop an unbiased pulse-oximetry method for assessing arterial oxygen saturation. The research addresses documented disparities in conventional pulse-oximetry readings across...
The National Heart, Lung, and Blood Institute (NHLBI) awarded Arkansas Children's Research Institute a $184,882 Project Grant effective June 1, 2026, through May 31, 2031, under the Cardiovascular Diseases Research program (CFDA 93.837). The ECLIPSE study (Extent and Clinical Impact of Pigment in Pulse Oximeter Saturation Error in ICU Infants) investigates measurement accuracy issues in pulse oximetry devices used to monitor oxygen saturation levels in critically ill preterm infants. Preterm infants with underdeveloped lungs are particularly vulnerable to complications from both insufficient and excessive oxygen delivery, making accurate oxygen saturation monitoring critical to clinical outcomes. This research addresses a significant clinical gap by examining how pigmentation-related variables may affect pulse oximeter readings in the neonatal intensive care setting. The project will be conducted at Arkansas Children's Research Institute's facility in Little Rock, Arkansas. As a pediatric medical research institution with extensive experience in federal-funded clinical research, ACRI will deliver specialized scientific investigations and clinical analyses supporting the study objectives through the five-year project period. The NHLBI funding supports basic and clinical research aimed at preventing and treating heart, lung, and blood disorders, with this award contributing to improved diagnostic and monitoring capabilities for vulnerable pediatric populations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $184.9k | 5/26/26 |