Project Grant K01AR085195
- Federal Grant Award Summary The Hospital for Special Surgery Fund, Inc. (HSS Foundation) received a $267,423 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), awarded September 16, 2025, with completion targeted for August 31, 2028. The grant funds research to develop circulating cell-free tumor DNA (ctDNA) biomarkers for assessing immunosuppressive drug...
- Federal Project Grant Award Summary The Hospital For Special Surgery Fund, Inc. (HSS Foundation) received a $445,217 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective September 1, 2025, through August 31, 2030. This five-year research initiative focuses on elucidating the regulatory mechanisms of osteoclasts, the multinucleated cells...
- Federal Project Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded $175,373 to The Hospital for Special Surgery Fund, Inc. on July 1, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). This K23 career development award supports Dr. Medha Barbhaiya's research focused on assessing risk for poor outcomes in antiphospholipid syndrome (APS). The project will deliver three primary products: (1)...
- Federal Grant Award Summary Brigham & Women's Hospital Inc. received a $746,572 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) on September 5, 2025, with completion targeted for August 31, 2030. The project, "Discovering and Characterizing the Germline Mechanisms of Cutaneous Immune-Related Adverse Events (CIRAE)," aims to investigate the...
- Federal Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $172,034 Project Grant to the University of Nebraska Medical Center on August 15, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). This research initiative, with a completion date of June 30, 2030, focuses on identifying molecular and epidemiologic determinants of myocardial dysfunction and heart failure (HF) in patients with...
- Federal Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded Massachusetts General Hospital a $165,240 Project Grant (CFDA 93.846: Arthritis, Musculoskeletal and Skin Diseases Research) effective June 1, 2026 through May 31, 2031. The grant supports a systems immunology research initiative investigating shared and unique mechanisms of autoimmunity with particular focus on regulatory T cell (Treg) dysfunction in lupus. The research...
- Grant Award Summary The Hospital For Special Surgery Fund, Inc. (HSS Foundation) received a $296,093 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2025, through August 31, 2027. The award supports research investigating endothelial cell sphingosine-1-phosphate receptor 1 (S1PR1) and its role in shaping the autoimmune response and attenuating injury in experimental lupus nephritis. This...
- Federal Grant Award Summary National Jewish Health received a $388,025 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) on June 1, 2026, with an ultimate completion date of May 31, 2028. The award funds research to develop novel murine and human models that elucidate the role of aberrant T cell subsets in systemic sclerosis-related pulmonary fibrosis,...
- Federal Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $172,584 Project Grant to The Trustees of Columbia University in the City of New York to support a five-year career development program (September 1, 2025 – August 31, 2030) focused on identifying causal genes in systemic sclerosis (SSC) through multi-omics analyses. The funded research program aims to deliver scientific outputs including gene prioritization methodologies...
- Federal Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded Weill Medical College of Cornell University a $726,898 Project Grant (R01) effective August 1, 2025, through June 30, 2030, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). This research initiative, titled "Personalized Immunomonitoring to Understand Juvenile Dermatomyositis," is led by Principal Investigators Pascual and Wilson and...
Federal Grant Award Summary The Hospital For Special Surgery Fund, Inc. (HSS Foundation) received a $129,330 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective June 15, 2026, with a completion date of May 31, 2031. This K01 mentored research award supports Dr. Jannat-Khah's development as an independent investigator studying immune checkpoint inhibitor (ICI) treatment outcomes in patients with rheumatoid arthritis (RA) and melanoma using real-world data. The research addresses a critical evidence gap by examining immune-related adverse events (IRAEs), disease flares, overall survival, and hospitalization rates in autoimmune disease patients treated with ICIs—a population historically excluded from clinical trials. The project will leverage Komodo HealthMap, a large real-world dataset, to investigate comparative safety and efficacy outcomes between ICI-treated RA and non-RA melanoma patients, with particular focus on the effects of immunomodulatory treatments including glucocorticoids and disease-modifying antirheumatic drugs (DMARDs). Preliminary findings by the investigative team demonstrated no difference in overall survival between RA and non-RA patients with metastatic non-small cell lung cancer treated with ICIs after adjusting for steroid use, and identified dexamethasone as a significant confounder. The award will generate peer-reviewed publications, epidemiological analysis, and evidence-based clinical guidance to inform treatment decisions for cancer patients with pre-existing autoimmune conditions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $129.3k | 6/11/26 |