Project Grant FA95502310533

This $4.5 million project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke, under the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program, will fund research at Baylor College of Medicine from August 2022 to July 2025. The grant aims to advance understanding of how the neuromodulators acetylcholine and norepinephrine shape cortical responses and influence behavior. Researchers will study the spatial...

This federal Project Grant award from the National Institute of Mental Health (CFDA 93.242 Mental Health Research Grants) provides $460,855 to New York University School of Medicine to investigate the cellular and circuit mechanisms by which acetylcholine (ACh) promotes associative learning in the primary somatosensory cortex. The key objectives are to: 1) use fluorescent ACh sensors and chemogenetic techniques to study the magnitude and time course of ACh release during different phases of an...

The University of California, Berkeley received a $2,611,308 Project Grant from the National Institutes of Health Trans-NIH Research Support program to investigate how neuromodulation shapes the fluidity of spatial working memory. The grant will fund research from September 2022 through August 2025 to advance understanding of how working memory circuits balance flexibility and stability. Researchers will use Drosophila melanogaster, the fruit fly, as an experimental model to define the neural...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $252,666 to The Trustees of Columbia University in the City of New York to conduct research on the role of functional modularity in the neural code underlying contextual behavior. The award will fund a combination of mathematical theory, artificial neural network modeling, and...

This cooperative agreement from the National Institute of Neurological Disorders and Stroke will fund $8,473,173 for research exploring the neural population codes that support context-dependent behavior. The funding will support a collaborative project between New York University, Riken, and Ecole Normale Superieure from April 15, 2021 through March 31, 2024 under the National Institutes of Health's Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA...

This two-year, $140,108 project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will fund research into the co-regulation of striatal dopamine and acetylcholine in associative reward learning. The grantee, The Trustees of Columbia University in the City of New York, will investigate how these two neuromodulators interact to drive associative reward learning processes. Specifically, the researchers will test the hypothesis that striatal...

This federal Project Grant award of $673,581.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research by New York University School of Medicine to investigate the neurobiological mechanisms underlying statistical learning. The research aims to build a comprehensive, circuit-level understanding of how the hippocampus and cortex interact to enable fundamental...

This three-year project grant from the Department of Health and Human Services National Institutes of Health provides $3,555,862 to The Trustees of the University of Pennsylvania under the Trans-NIH Research Support program (CFDA 93.310) to study the interactions between the locus coeruleus-norepinephrine system and the dorsolateral prefrontal cortex in flexible decision-making. Specifically, the researchers will train monkeys on a novel task to quantify how learned expectations and new...

The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded the University of Southern California a $14.16 million cooperative agreement from April 2021 through March 2024 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award will support research to develop a theoretical model describing the neural circuits underlying threat detection and how they can change as a result of associative...

This $2.3 million project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will fund research on hippocampal-cortical contributions to spatial learning and memory in freely behaving macaques. Over a three-year period from May 2022 to April 2025, researchers at Vanderbilt University will use high-density wireless recordings to test predictions from complementary learning systems theory regarding the roles of hippocampal subregions and...