Project Grant F32DK146553
- Federal Grant Award Summary AdventHealth Orlando received a $248,322 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded on March 1, 2026, with completion scheduled for February 28, 2029. This research grant funds a translational study designed to determine cell- and spatially-distinct skeletal muscle transcriptional aberrations associated with insulin...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Boston University Medical Campus a Project Grant of $817,498 on February 18, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award extends through January 31, 2031, and supports extramural basic biomedical research investigating the mechanisms of adipose tissue remodeling and metabolic dysfunction in obesity....
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded $140,116.00 to the Beckman Research Institute of the City of Hope on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to support basic biomedical research on gut-fat crosstalk in metabolic regulation through July 31, 2028. The research project investigates the mechanisms of communication between the intestine...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded $150,583 to Joslin Diabetes Center, Inc. under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) on September 15, 2025, for a project period extending through July 31, 2028. The grant funds research to identify the primary molecular drivers of insulin resistance and sex-specific alterations in glucose uptake ability. Utilizing induced...
- Federal Project Grant Award Summary The University of Florida Division of Sponsored Research received a $795,806 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) on May 20, 2026. The award funds research to elucidate the molecular mechanisms by which the glucocorticoid receptor integrates stress responses from fasting and exercise in skeletal muscle...
- Federal Project Grant Award Summary The University of Virginia received a $782,459 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective March 1, 2026 through February 28, 2031. The award funds research investigating the mechanisms by which obesity exacerbates cardiovascular disease (CVD) risk in individuals with Type 1 Diabetes (T1D), specifically...
- Federal Grant Award Summary The University of Chicago received a $123,000 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded on June 16, 2026, with completion scheduled for May 31, 2028. This award funds basic biomedical research to characterize adipocyte (fat cell) heterogeneity and understand how diverse adipose tissue cell populations respond to...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $786,216 Project Grant to the University of California, Los Angeles (UCLA) on August 28, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports a four-year research initiative (through June 30, 2029) investigating post-transcriptional regulation of hepatokines and systemic metabolism. The research focuses on identifying...
- Federal Project Grant Award Summary The University of Massachusetts Medical School received a $2.64 million Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 1, 2025, through August 31, 2029. This award funds biomedical research investigating novel mitochondrial mechanisms underlying obesity pathogenesis, with specific focus on...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Johns Hopkins University a Project Grant of $116,625 effective July 1, 2026 through June 30, 2028 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports a two-year secondary data analysis research initiative to identify and validate novel cardiometabolic subtypes in individuals with prediabetes using machine-learning methods. The...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $149,264 Project Grant to AdventHealth Orlando on August 27, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). This award funds a three-year clinical research study examining the effects of endurance exercise training on adipocyte heterogeneity in adults with obesity. The research will utilize the institution's Translational Research Institute infrastructure, including metabolic testing capabilities such as hyperinsulinemic euglycemic clamps and adipose tissue biopsy protocols, to investigate whether a three-month endurance training intervention improves a metabolically favorable adipocyte subtype (adipocyte-2) and its associated transcriptional profiles, independent of weight loss. The project aims to elucidate cellular and molecular mechanisms by which exercise enhances lipid storage capacity and cardiometabolic health in obese populations. The study deliverables include two primary research aims: Aim 1 will characterize the relationship between adipocyte-2 abundance, transcriptional profiles, and spatial localization with insulin sensitivity using abdominal subcutaneous adipose tissue microdialysis and functional adipocyte assays; Aim 2 will investigate whether endurance training increases adipocyte-2 abundance and alters its positioning within adipose tissue in relation to endothelial cells and pericytes. Research findings are expected to contribute to improved understanding of how exercise-induced adaptations in adipose tissue function enhance metabolic health outcomes in individuals with obesity.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $74.6k | 2/27/26 | ||
| Not listed | $0 | 2/27/26 | ||
| Not listed | $74.6k | 2/27/26 |