Project Grant F32AI200531
- The National Institute of General Medical Sciences awarded Georgia TECH Research Corp $393,500 on August 24, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate how commensal gut protists shape microbiome community ecology and function. Over five years through April 30, 2031, the Lind Laboratory at Georgia Tech will examine gut protist metabolism, identify nutritional inputs and outputs, annotate metabolic gene function, and determine how protist...
- The National Institute of Allergy and Infectious Diseases awarded the University of Georgia Research Foundation $228,000 on July 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop enzymatic pipelines for the in vitro synthesis of parasitic glycosylphosphatidylinositol (GPI) anchors and GPI-anchored proteins. Parasitic infections affect more than one billion people globally. GPI anchors and GPI-anchored proteins are essential to parasite cell surfaces and...
- The National Institute of Allergy and Infectious Diseases awarded $157,356 to the University of Georgia Research Foundation, Inc. on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct strain-resolved metagenomics analysis of Bifidobacterium infantis colonization in early infancy and its associations with child health outcomes. The research generates shotgun metagenome data from biobanked infant stool samples collected through the ECOMID birth...
- The National Institute of Allergy and Infectious Diseases awarded Georgia State University Research Foundation Inc. $795,962 on August 4, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate how gut microbiota composition influences respiratory viral infection outcomes and alveolar macrophage function. The research examines the protective mechanisms by which segmented filamentous bacteria (SFB) colonization in the intestine confers resistance to severe...
- The National Institute of Allergy and Infectious Diseases awarded the University of Georgia Research Foundation, Inc. $190,000 on September 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to identify Plasmodium liver-stage secreted effector proteins that enable parasite survival and immune evasion in hepatocytes. The project will map the secretome and interactome of Plasmodium falciparum and Plasmodium berghei in hepatocytes using proximity-dependent...
- The National Institute of Allergy and Infectious Diseases awarded Georgia TECH Research Corp $149,190 on January 23, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate R-pyocins as a therapeutic approach to treat high-risk, multidrug-resistant Pseudomonas aeruginosa wound infections. The project addresses the rising prevalence of multidrug-resistant and extensively drug-resistant P. aeruginosa strains that cause acute and chronic infections from...
- The National Institute of Allergy and Infectious Diseases awarded the University of Georgia Research Foundation $228,000 on September 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855, Assistance Listing Project Grant R21AI202296). The award funds research determining the relationship between Trypanosoma cruzi parasite genetics and pathogen burden in infected hosts. The project addresses gaps in understanding why approximately 30% of T. cruzi-infected humans...
- The National Institute of Allergy and Infectious Diseases awarded $400,932 to the University of Georgia Research Foundation, Inc. on February 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support research into immunity induced by cryptococcal morphological strains in CD4+ T cell-deficient hosts. The research addresses cryptococcal meningoencephalitis, which accounts for more than 15 percent of total AIDS-related deaths globally, with mortality rates...
- The National Institute of Allergy and Infectious Diseases awarded Georgia TECH Research Corp $410,864 on February 19, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate mechanosensing through the B cell antigen receptor. The recipient will characterize isotype-dependent in situ affinities and force-dependent lifetimes of B cell antigen receptor (BCR)–antigen bonds at the single-cell and single-bond level, correlating concurrent calcium flux measurements...
- The National Institute of Allergy and Infectious Diseases awarded the University of Georgia Research Foundation, Inc. $675,790 on August 7, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct molecular analysis of transcription termination by RNA polymerase II in trypanosomatids. The research investigates epigenetic mechanisms of gene expression control in Trypanosoma brucei and Leishmania species, protozoan parasites that cause human African sleeping...
The National Institute of Allergy and Infectious Diseases awarded Georgia TECH Research Corp $152,600 on December 9, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate how Blastocystis, the most prevalent protist in the human gut microbiome, shapes gut ecosystem function and community structure. The research comprises three aims. Aim 1 examines how Blastocystis metabolizes dietary lipids through biochemical assays, microscopy-based trafficking analysis, and transcriptomic identification of genes involved in lipid transport and metabolism, building on preliminary evidence that lipid-rich conditions promote growth and that people colonized with Blastocystis have lower serum triglyceride levels. Aim 2 investigates how Blastocystis modulates microbiome composition by releasing metabolic byproducts—specifically succinate and hydrogen—through quantification of metabolite production, microbial response testing, and targeted metabolomics to identify cross-feeding relationships. Aim 3 explores cooperative and competitive interactions between Blastocystis and saccharolytic bacteria, including fiber-degrading specialists and generalists, using co-culture experiments and microcosms to assess microbial fitness and metabolite exchange. Performance occurs in Atlanta, Georgia, with a period of performance through August 31, 2029. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $76.3k | 6/10/26 | ||
| Not listed | $76.3k | 6/10/26 | ||
| Not listed | $0 | 6/10/26 |