Project Grant F32AI104252

This $1,480,500 federal Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) will fund research by The Trustees of Columbia University in the City of New York to identify and characterize the roles of non-coding RNAs in regulating drug-induced quiescence in Plasmodium falciparum, the parasite that causes malaria. The project aims to uncover novel epigenetic and epitranscriptomic mechanisms that enable...

Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston Children's Hospital a Project Grant of $501,800 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 4, 2025 through July 31, 2027. This award supports investigator-initiated biomedical research focused on elucidating the molecular structure and mechanisms of the Plasmodium basal complex using cryo-electron tomography (cryo-ET). The research addresses...

Grant Award Summary Renovate Biosciences Inc. received a $584,232 Project Grant awarded on September 25, 2025, by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports the BLIPS (Biocompatible Liver in Pigs) project, which aims to develop xenotransplantation technology to generate human liver tissue from patient-specific donor cells using pigs as bio-incubators....

Federal Project Grant Award Summary Hepatx Corporation received a $175,964 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded on May 13, 2025, with completion targeted for April 30, 2027. The company will develop and validate a proteomic blood test to monitor the success of transplanted hepatocytes in human patients. Using mass spectrometry methods to...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $360,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Virginia Polytechnic Institute & State University (Virginia Tech) to develop a gerbil model to delineate the mechanism of Hepatitis E Virus (HEV) extrahepatic pathogenesis. The key objectives are to: 1) Determine the effect of HEV-3-induced pyroptosis in neurovascular unit (NVU) cells and identify the mechanisms of...

This Project Grant, awarded on September 1, 2025, by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), provides $395,471 in federal funding to the Research Foundation of The City University of New York (Lehman College) to support fundamental biomedical research addressing malaria-associated acute kidney injury (MAKI) and its progression to chronic kidney disease (CKD). The research addresses a critical global...

Federal Cooperative Agreement Summary Harvard College, through its Office for Sponsored Programs Division, received a $17.8 million Cooperative Agreement from the Advanced Research Projects Agency for Health (ARPA-H, CFDA 93.384) on September 26, 2025, to develop an off-the-shelf engineered liver tissue product to address the critical shortage of donor organs for liver transplantation. The primary objective is to create a universal, transplant-ready graft utilizing next-generation technologies...

Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $545,236 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for research on heme homeostasis in the malaria parasite Plasmodium falciparum. The award, effective July 16, 2025, through January 31, 2027, supports investigator-initiated biomedical research addressing infectious diseases and related mechanisms. The research will be...

This $1.59 million Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded to New York Blood Center, Inc. on August 1, 2025, funds a four-year research initiative (through April 30, 2029) investigating the role of erythroblastic island macrophages (EBIMs) in normal and disordered red blood cell production. The research focuses on defining the mechanisms by which EBIMs support normal erythropoiesis and...

Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $895,740 Project Grant to The Regents of the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 2, 2026, with a completion date of January 31, 2031. This award supports research to characterize CD4 T cells targeting liver and blood stage malaria epitopes, addressing critical gaps in malaria vaccine development....