Differences in adverse perinatal outcomes and the impact of hazardous heat in the united states

Active Project Grant Awarded Last action

Award ID
F31ES039191
Recipient
Awarding agency
Obligated
$89,466

Award facts

Assistance listing
93.113 Environmental Health
Completion date 0% complete
Originally
Place of performance
New York, NY 10032, USA

Award details come from USAspending.gov.

Description

Abstract
Adverse perinatal outcomes, including maternal conditions (e.g., gestational hypertension), delivery characteristics (e.g., preterm birth), and postnatal interventions (e.g., neonatal intensive care unit (nicu) admission), remain a critical public health concern in the united states, affecting an estimated 1.2 million births in 2023. These outcomes contribute to infant mortality and long-term neurodevelopmental and chronic disease risks, with persistent differences across sociodemographic groups and geography. Hazardous heat is a leading cause of weather-related morbidity and mortality in the united states and may negatively affect perinatal health through maternal dehydration, impaired placental function, and inflammatory response during critical periods of gestation. However, national evidence linking heat to a broad spectrum of maternal and neonatal outcomes is limited. Prior research has focused primarily on preterm birth and birthweight, relied on dry temperature metrics, and provided little evidence on population-level differences or long-term patterns. The objective of this F31 fellowship is address these research gaps by evaluating national patterns in a broad spectrum of adverse perinatal outcomes, including maternal conditions, delivery characteristics, and postnatal complications and interventions, and quantifying the impact of hazardous heat exposure using complete U.S. Natality records during 2014-2024 linked with high-resolution dry temperature and wet-bulb globe temperature estimates. Aim 1 will characterize annual county-level trends in adverse perinatal outcomes using bayesian spatiotemporal models, estimating differences by maternal demographics and geography. Aim 2 will determine trimester-specific associations between hazardous heat and temperature-sensitive perinatal outcomes (i.e., gestational hypertension, gestational diabetes, gestational age, birthweight, apgar score, assisted ventilation, nicu admission) and estimate the hazardous heat-attributable fraction. Aim 3 will apply a synthetic control framework to estimate long-term, population-level impacts of hazardous heat exposure on annual rates of adverse outcomes. The fellowship training plan is designed to strengthen expertise in (1) environmental epidemiology and perinatal health; (2) advanced bayesian modeling and spatiotemporal models; (3) causal inference using synthetic control methods; and (4) extreme-weather exposure assessment. Training will be supported through structured coursework and individualized mentorship within the columbia university environmental health sciences department, the sustainable public health through advocacy resilience and knowledge (spark) lab, and the columbia center for children's environmental health. The proposed research and training program aligns with niehs priorities in data science and computational biology (area 4), protecting health from the impacts of extreme weather and disasters (area 5), and environmental health disparities (area 6). Findings will advance understanding of how hazardous heat impacts perinatal health and inform clinical guidance and extreme weather adaptation strategies to protect maternal and neonatal health.

Transactions

Action Obligated Date
Amendment $0
Amendment $0
Original award $44,733

Quick answers

Who received award F31ES039191?

F31ES039191 was awarded to The Trustees Of Columbia University In The City Of New York by National Institute of Environmental Health Sciences (National Institutes of Health) on January 25, 2027.

How much is award F31ES039191 worth?

$89,466 has been obligated on F31ES039191.

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