Acculturation and aging: multidimensional insights into alzheimer's disease knowledge and memory performance
Active Project Grant Awarded Last action
- Award ID
- F31AG099593
- Recipient
-
The Trustees Of Columbia University In The City Of New York UEI QHF5ZZ114M72
- Awarding agency
-
National Institute on Aging
National Institutes of Health, Department of Health and Human Services
- Obligated
- $50,114
Award facts
- Assistance listing
- 93.866 Aging Research
- Completion date 0% complete
- Place of performance
- New York, NY 10032, USA
Award details come from USAspending.gov.
Description
- Abstract
- Acculturation, the multidimensional process through which individuals adapt to new cultural environments, influences health behaviors, healthcare access, and cognitive outcomes. Yet its relationship with alzheimer's disease (ad) knowledge and memory performance remains poorly understood, in part because most studies rely on unidimensional proxies such as nativity or survey language. These simplified measures obscure heterogeneity in cultural adaptation and hinder efforts to reduce dementia disparities among latinos, the second-largest U.S. Population. This project leverages data from the información DE LA enfermedad DE alzheimer para latinos (IDEAL) study, a randomized clinical trial examining the psychosocial, behavioral, and cognitive impacts of apoe genotype disclosure. Using a multidimensional, socioecological framework to categorize participants into acculturation profiles based on migration and cultural variables, the proposed research will: (1) assess how these profiles relate to knowledge and beliefs about ad, testing whether latino origin subgroup modifies these effects; and (2) estimate the causal effect of apoe-Ε4 carrier status on longitudinal subjective and objective memory outcomes, testing whether acculturation profile modifies these effects. To achieve these aims, the proposed study will build on a latent class analysis that identified three distinct acculturation profiles: traditional immigrant, traditional bicultural, and integrated bicultural. Differences in ad knowledge and beliefs will be modeled using multivariate linear and logistic regression. For memory outcomes, targeted maximum likelihood estimation (TMLE) will be used to estimate interpretable, counterfactual effects of apoe-Ε4 carrier status and to test whether these effects vary across acculturation profiles. Findings will clarify how sociocultural context shapes ad knowledge and memory performance and will identify culturally relevant targets for improving education, risk communication, and early detection among diverse latino communities. This F31 fellowship will provide comprehensive training in acculturation theory, neuroepidemiology, and advanced causal inference, supported by an interdisciplinary mentorship team at columbia university. Through structured coursework, mentored research, and professional development, the fellowship will prepare me for an independent research career dedicated to reducing cognitive health disparities and advancing NIA's mission to optimize health and well-being in aging populations.
Quick answers
Who received award F31AG099593?
F31AG099593 was awarded to The Trustees Of Columbia University In The City Of New York by National Institute on Aging (National Institutes of Health) on February 25, 2027.
How much is award F31AG099593 worth?
$50,114 has been obligated on F31AG099593.
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