Project Grant F30MH144778
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded $200,538 to The Trustees of The University of Pennsylvania under CFDA 93.242 (Mental Health Research Grants) on December 14, 2025, with a completion date of June 30, 2027. The project, "Mapping the Functional Organization of the Cortex Across Development: The Principal Hierarchy and Transdiagnostic Psychopathology Risk," delivers research services investigating the relationship between abnormal...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $221,302 Project Grant to the University of Pennsylvania on March 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to assess the impact of mandatory neuroethics requirements on National Institutes of Health (NIH)-funded neuroscience research. This two-year exploratory R21 project, with completion scheduled for February 29, 2028, directly addresses the NIH's 2025 initiative to enhance...
- The University of Delaware received a $182,436 Project Grant awarded on October 12, 2025, from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). This research initiative examines neural network disturbances underlying the co-occurrence of depression and anxiety in adolescents through advanced neuroimaging analysis. Rather than focusing on isolated brain regions, the project employs a network perspective using graph theory and...
- Federal Grant Award Summary The University of Pennsylvania received a $762,440 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), effective April 1, 2026 through January 31, 2031. The grant supports research to develop and validate a concurrent transcranial magnetic stimulation/functional magnetic resonance imaging (TMS/fMRI) protocol that assesses the neurobiological mechanisms of continuous theta burst...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $124,128 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded December 15, 2025, with a completion date of December 14, 2031. This award funds a longitudinal neuroimaging research study investigating how structure-function (S-F) coupling in human brain networks changes from birth through adolescence and its relationship to...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Trustees of The University of Pennsylvania a $689,249 Project Grant (CFDA 93.242: Mental Health Research Grants) on April 15, 2026, to investigate sex-specific mechanisms by which maternal immune activation (MIA) during pregnancy impacts cortical development and elevates risk for neurodevelopmental disorders (NDDs). The research, which extends through January 31, 2031, focuses on elucidating the role of the...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Pennsylvania a $2,693,038 Project Grant under the Mental Health Research Grants program (CFDA 93.242) for the period September 1, 2025 through August 31, 2029. The award funds research investigating the role of striatal interneurons in behavioral control and value-based decision-making. The project will employ viral-genetic tools and a head-fixed, value-based choice task to systematically examine...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $761,595 to the University of Michigan, effective June 1, 2026 through March 31, 2031, under the Mental Health Research Grants program (CFDA 93.242). The research project, titled "Evaluating Efficiency of Evidence Accumulation as a Neurodevelopmental Mechanism of Transdiagnostic Risk for Psychopathology: A Computational Model-Based Approach," delivers basic neuroscience...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $197,600 Project Grant to The Trustees of The University of Pennsylvania on September 21, 2025, under the Mental Health Research Grants program (CFDA 93.242). The award supports research aimed at differentiating primary and secondary subtypes of callous-unemotional (CU) traits during early childhood through an ongoing longitudinal study extending to June 30, 2028. The research investigates how distinct...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded University of Colorado-Denver $429,000 under the Mental Health Research Grants program (CFDA 93.242) for a two-year exploratory research project spanning June 1, 2025 through May 31, 2027. The project, titled "A Synaptogenic Adhesion Code for Myelin Specificity," investigates the molecular mechanisms underlying myelin formation and white matter abnormalities associated with autism spectrum disorder (ASD)...
The National Institute of Mental Health (NIMH) awarded the University of Pennsylvania a $110,228 Project Grant under the Mental Health Research Grants program (CFDA 93.242) on November 4, 2026, with completion scheduled for May 31, 2029. The grant supports research mapping person-specific and spatially precise white matter (WM) development in relation to transdiagnostic psychopathology and polygenic risk for psychiatric disorders. The project leverages data from the large, longitudinal Adolescent Brain Cognitive Development (ABCD) Study (N=11,875; ages 9-16), which includes multi-shell diffusion MRI, clinical assessments, and genotype data. The research delivers two primary investigative products: (1) characterization of within-individual, along-tract WM development patterns and evaluation of associations between transdiagnostic psychiatric symptoms and superficial WM regions adjacent to higher-order association cortices; and (2) assessment of how polygenic risk scores for transdiagnostic psychiatric illness relate to spatially precise WM microstructure metrics. The deliverables advance understanding of neurobiological mechanisms linking WM maturation, psychiatric symptomatology, and genetic liability for transdiagnostic mental illness by identifying specific brain regions where protracted WM development correlates with psychiatric risk and symptom expression during adolescence.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $55.1k | 5/7/26 | ||
| Not listed | $55.1k | 5/7/26 | ||
| Not listed | $0 | 5/7/26 |