Project Grant E1217896

The Ovitz Corporation received a $612,342 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) to develop artificial intelligence-driven tools for automating the design of higher-order aberration optics in scleral contact lenses. Beginning September 1, 2025, and concluding August 31, 2026, the project aims to reduce lens design time by up to 40 minutes per lens and eliminate at least one patient fitting session by implementing a machine learning...

Federal Grant Award Summary Oregon Health & Science University received a $1.73 million project grant from the National Eye Institute (Vision Research program, CFDA 93.867) awarded September 1, 2025, with completion scheduled for April 30, 2030. This multidisciplinary research initiative will develop next-generation optical imaging technologies and functional biomarkers for assessing photoreceptor health and visual function in retinal degeneration. The project addresses a critical clinical...

Federal Grant Award Summary The National Eye Institute (NEI) awarded The Washington University a Project Grant totaling $427,625 under the Vision Research program (CFDA 93.867) for the period of April 1, 2026, through March 31, 2028. The award supports development of novel statistical methodologies to improve detection and characterization of visual field progression in primary open-angle glaucoma (POAG) using data from the Ocular Hypertension Treatment Study (OHTS). The research will produce...

Cooperative Agreement Summary The Ohio State University received a $9.08 million Cooperative Agreement from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), awarded September 15, 2025, with completion targeted for July 31, 2030. The award funds the Data Coordinating Center for the Delaying the Onset of Nearsightedness (DONUT) Study, a multicenter randomized clinical trial designed to evaluate whether 0.05% atropine eye drops can delay myopia onset and slow...

Federal Project Grant Award Summary Eye C Better Corp received a $315,825 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective September 1, 2025 through August 31, 2026. The award funds development of a novel, non-invasive intraocular pressure (IOP) measurement technology called Photonic IOP Biomonitoring (PIB) designed to address glaucoma management challenges. Glaucoma affects over 5 million Americans and costs the U.S. economy...

Federal Project Grant Award Summary The National Eye Institute (NEI) awarded Oregon Health & Science University (OHSU) a Project Grant totaling $875,918 under the Vision Research program (CFDA 93.867) to develop, evaluate, and validate Large Language Models (LLMs) for extracting clinical data from electronic health records (EHRs) related to amblyopia treatment and outcomes. The project, which runs from August 1, 2025, through July 31, 2027, addresses a critical research challenge: amblyopia,...

Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $437,250 to the University of California, San Diego to develop an integrated bioprinting and optogenetics platform for evaluating neural activity in stem cell-derived retinal disease models. The award, effective September 1, 2025, through August 31, 2027, supports research aimed at creating a "visual-circuit-on-a-chip" by integrating three-dimensional (3D)...

Summary The National Eye Institute awarded a $1.01M Vision Research grant (CFDA 93.867) to Washington University in St. Louis beginning July 1, 2025, through March 31, 2030. The project, titled "Visual Feature Competition Between Central and Peripheral Retinal Pathways," will deliver fundamental neuroscience research investigating how the retina processes competing visual signals that control eye fixation and the optokinetic reflex (OKR). The primary products include empirical findings...

Summary The National Eye Institute awarded a Cooperative Agreement totaling $360,524 to the University of California, San Diego (awarded September 15, 2025, with completion targeted for June 30, 2028) under the Vision Research program (CFDA 93.867) to establish and maintain expert curation of clinically significant genetic variants associated with early-onset retinal degeneration diseases. The primary deliverable is the development and operation of a Variant Curation Expert Panel (VCEP) within...

Federal Grant Award Summary This National Eye Institute (NEI) Vision Research program (CFDA 93.867) Project Grant award of $574,158 to Cleveland Clinic Lerner College of Medicine of Case Western Reserve University supports a five-year research initiative (September 1, 2025 through April 30, 2030) investigating the role of melanopsin in photoreceptor outer segment renewal. The research will produce empirical findings and mechanistic insights into how melanopsin, a photosensitive protein expressed...