Project Grant DTFH6110G00006

This Project Grant from the National Institutes of Health's National Cancer Institute totaling $668,151 will support the development of highly multiplexed live-cell G protein-coupled receptor (GPCR) arrays for glioma drug discovery. Spectragenetics, Inc. will deploy an automated multiplexed live-cell assay to detect and quantify agonist and inverse-agonist activities against 55 GPCRs known to be upregulated or downregulated in human gliomas. The assay will be used to screen 48 established...

This $455,824.20 Project Grant from the National Center for Advancing Translational Sciences will fund research to identify direct interactions between understudied G protein-coupled receptors (GPCRs) and protein kinase A (PKA) isoforms. The University of Utah will utilize the National Institutes of Health's existing Prestwick Chemical Library and NanoBRETT kinase assay platforms to develop a high-throughput screening assay for GPCR-PKA interactions. This assay will then be applied to...

The Substance Abuse and Mental Health Services Administration (SAMHSA) awarded a $109,846 Formula Grant under the Projects for Assistance in Transition from Homelessness (PATH) program (CFDA 93.150) to the Guam Behavioral Health & Wellness Center (GBHWC). The grant will support comprehensive services for individuals in Guam experiencing serious mental illness, co-occurring substance abuse disorders, and homelessness or imminent risk of homelessness. Funded services include outreach,...

This Project Grant awarded by the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) provides $2,218,222.00 to conduct a randomized clinical trial evaluating the efficacy of brain games and transcranial electrical stimulation in improving cognitive and functional outcomes for active duty service members and veterans with mild traumatic brain injury. The key products/services to be delivered include a four-arm Phase 2 clinical trial...

This Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $1,002,591.00 to Targepeutics, Inc. to determine the intratumoral drug distribution of the immunotoxin GB13 for the treatment of adult and pediatric brain cancers. The 3-year project aims to transform health care for Service Members and the American public through innovative and impactful biomedical research on medical solutions for the battlefield. The...

Federal Grant Award Summary The Guam Police Department received a $1.24 million Project Grant from the Department of Justice's Community Oriented Policing Services (COPS) Anti-Methamphetamine Program (CFDA 16.072) on October 1, 2025, with a completion date of September 30, 2028. This three-year award funds investigative operations and task force activities targeting illicit methamphetamine manufacturing, distribution, and precursor chemical diversion schemes within Guam's jurisdiction. The...

The Institute of Gas Technology (IGT) was awarded a $200,000 Project Grant from the Department of Transportation Pipeline and Hazardous Material Safety Administration (PHMSA) under the Interagency Hazardous Materials Public Sector Training and Planning Grants program (CFDA 20.703) to deliver hazardous materials emergency preparedness services. The Hazardous Materials Emergency Preparedness Grant (HMEP) aims to increase effectiveness in safely handling hazardous materials incidents and enhance...

This three-year, $900,000 Project Grant from the Department of Justice Office of Justice Programs Office of Juvenile Justice and Delinquency Prevention will support Los Angeles Team Mentoring Inc.'s expansion of its mentoring programs in California under the Juvenile Mentoring Program (JMP; CFDA 16.726). LATM will recruit and train 864 mentors to provide in-person and virtual mentoring to 3,204 at-risk middle school youth across the Los Angeles and San Diego Unified School Districts. The...

The National Center for Advancing Translational Sciences (NCATS), under CFDA Program 93.350, has awarded a $331,034 Project Grant to Vector Surgical LLC to develop the Gene Therapy Catheter (GTC) - an electrical pulsing device designed to enhance the delivery of adeno-associated virus (AAV) gene therapy to the liver. The GTC aims to improve the efficiency and safety of liver-directed gene therapies by combining local delivery with electrical pulsing and a double-balloon system to isolate the...

Federal Project Grant Award Summary The University of California, San Diego received a $398,750 Project Grant award from the National Center for Advancing Translational Sciences (NCATS, CFDA 93.350) to support translational research on HPDL deficiency, a novel mitochondrial encephalopathy affecting approximately 40 U.S. patients. The award, effective August 20, 2025, through July 31, 2027, funds a natural history study enrolling 10 patients with neurodevelopmental disorder with progressive...