Project Grant 90BISB0031

The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121), has awarded a $306,633 Project Grant to Ther-Ai LLC to develop CRANIAMAP, a software suite for automated segmentation and landmarking of cone-beam computed tomography (CBCT) scans. The goal of this SBIR Phase I project is to create a robust, comprehensive solution that can dramatically enhance the speed and accuracy of critical diagnostic...

This National Science Foundation (NSF) Cooperative Agreement award, provided through the NSF Technology, Innovation, and Partnerships (CFDA #47.084) program, funds the development of a novel, fully implantable craniofacial distraction system by Ostiio LLC, a medical device company based in Philadelphia, PA. The $1,000,000 award aims to produce a magnetic, subcutaneous distraction device capable of gradually correcting skeletal abnormalities affecting craniomaxillofacial functions such as...

This $672,394.58 project grant from the National Institutes of Health's National Institute of Dental and Craniofacial Research Oral Diseases and Disorders Research program (CFDA 93.121) supports the development of a crosslinkable tissue particle implant for regenerating craniofacial bone. Led by Leefa Biotech LLC, the one-year award aims to demonstrate improved bone regeneration in critical-size cranial bone defects using the implant compared to the current standard of care. If successful, the...

The National Institute of Child Health and Human Development (NICHD) awarded a $295,907 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Liberating Technologies Inc. (LTI) to develop a prototype "Unintrusive Pediatric Logging Orthosis Analytic Device (UPLOAD)." The goal is to create a commercially viable, unobtrusive remote monitoring system for pediatric orthotics that can improve compliance tracking. Key features include long battery life, low...

The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $304,723 Project Grant under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program to Qualia Oto, Inc. of Dallas, Texas. The project aims to assess the viability of robotic-assisted, shape-conforming cochlear implant (CI) electrode arrays as a new solution for achieving atraumatic cochlear implantation and optimal electrode positioning. The research encompasses establishing a...

This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $232,230 to the Regents of the University of Michigan to develop and evaluate a novel ankle-foot orthosis (AFO) design. The key objectives are to improve upon an existing variable stiffness orthosis (VSO) by incorporating a unique cam-based transmission that allows for decoupled energy...

This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $313,000 to Emory University to develop a novel zebrafish model of syndromic craniosynostosis. The research aims to comprehensively characterize the phenotypic, cellular, molecular, and genetic changes in this unique craniosynostosis mutant zebrafish model. This includes evaluating skeletal development, bone...

This SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Rehabnetics Medical LLC to develop a robotic wrist-hand exoskeleton device for physical therapy. The project aims to create a prototype system that can provide tailored rehabilitative exercises based on quantified measures of a patient's motor function recovery. Key technical milestones include developing objective diagnostic markers, an...

The National Institute of Child Health and Human Development (NICHD) awarded a 2-year, $458,397 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Trustees of Columbia University in the City of New York. The funding will support research to characterize head control impairments in individuals with severe Cerebral Palsy (CP) and test the feasibility of a multi-session motor training program using a robotic neck brace to promote postural...

The U.S. National Institute of Dental and Craniofacial Research (NIDCR) awarded a $250,931 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Children's Mercy Hospital in Kansas City, Missouri. The grant aims to develop a novel diagnostic modality integrating dynamic computed tomography (4D-CT) and computational fluid dynamics (CFD) to quantify upper airway obstruction severity in patients with Robin sequence, a congenital craniofacial condition. The project...