Project Grant 2638478
- Superior Nano LLC received a $512,000 National Science Foundation Project Grant to develop dense nanolipid fluid systems for delivering drugs with poor bioavailability. The NSF funding supports research from June 2022 to May 2023 under the Technology, Innovation, and Partnerships program. This award will allow Superior Nano to advance scientific understanding of surfactant-lipid-water systems and create new knowledge applicable to manufacturing drug nanoparticles using twin-screw extrusion. By...
- This $100,000 National Science Foundation project grant supports the development of a novel microencapsulation technique using a nature-derived biodegradable polymer at Cornell University from June 2022 through May 2023. The goal is to advance a microencapsulation method that protects oil-based materials in consumer products while addressing microplastics pollution. Currently, most commercial microencapsulation techniques rely on petroleum-based materials that do not degrade and contribute to...
- The Tiny Cargo Company received a $432,000 National Science Foundation Technology, Innovation, and Partnerships Project Grant to test the scalability of an exosome isolation technology for developing an orally administered radioprotective therapeutic. The goal is to establish proof-of-concept for a safe, orally delivered drug platform capable of transporting biologic and small molecule therapeutics to treat radiation damage and related diseases. The first year of the award will determine scaling...
- The National Science Foundation awarded Nanofresh LLC $305,000 on July 1, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop an edible, compostable nanocomposite coating that extends produce shelf life beyond current wax-coating performance while reducing postharvest loss and supporting food security. The project advances a micro- and nanoscale layered coating formulation from lab-scale results—which demonstrated shelf-life extension nearly tripling...
- Nostopharma LLC was awarded a $256,000 Small Business Technology Transfer Phase I Project Grant from the National Science Foundation to develop a sustained-release, biodegradable nanoparticle drug delivery system for treatment of soft tissue trauma complications. Funded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the 12-month project beginning March 1, 2022 aims to demonstrate in vitro and in vivo feasibility of modulating the ectopic bone microenvironment...
- The National Science Foundation (NSF) awarded a $1,000,000 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Soliome Inc., a small business located in San Francisco, CA. The grant supports the development of biocompatible and biodegradable ultraviolet (UV) filters for use in skincare, cosmetics, and sunscreen products. The project aims to create novel, safe UV materials as an alternative to current petroleum-based photo-protectants that can...
- Nano Pharmasolutions, Inc. received a $275,961 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041). The grant funds the development of a novel nanoformulation drug delivery platform to address challenges associated with poorly soluble drugs. The goal is to improve drug solubility and bioavailability through innovative formulation approaches. The one-year project period runs from August 1, 2021...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Delaqua Pharmaceuticals, Inc. aims to enhance the therapeutic use of hydrophobic drugs through a polymeric micelle approach to drug solubilization. The key objectives are to 1) improve the formulation of spherical micelles for enhanced stability and drug solubilization, 2) perform initial toxicity studies to establish the safety of the platform, and 3) demonstrate...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) award of $274,947 to Lattice Therapeutics Inc. supports the development of a customizable, next-generation RNA delivery particle. The project aims to validate the ability of an engineerable protein nanoparticle platform to efficiently and specifically deliver RNA cargoes to target cancer cells. Key objectives include in vitro evaluation of RNA...
- Federal Cooperative Agreement Summary Award: NSF SBIR Phase II: nCapsule Personalized Cancer Screening for Colorectal Cancer Treatment Regimens Funding Agency: National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) Program (CFDA 47.084) Awardee: Encapsulate Inc., Farmington, Connecticut Award Amount: $1,213,619 | Award Date: June 15, 2025 | Completion Date: May 31, 2027 Encapsulate Inc. is developing an integrated precision oncology platform that combines microfluidics,...
I-CORPS: TRANSLATION POTENTIAL OF A PLANT-DERIVED NANOCARRIER PLATFORM FOR IMPROVING THE STABILITY, DISPERSION, AND CONTROLLED DELIVERY OF BIOACTIVE COMPOUNDS -THIS I-CORPS PROJECT IS BASED ON THE DEVELOPMENT OF A NANOSIZED TRANSPORT SYSTEM USING PLANT MATERIALS TO STABILIZE AND DELIVER ACTIVE SUBSTANCES SUCH AS DRUGS. CURRENT DELIVERY SYSTEMS OFTEN SUFFER FROM POOR STABILITY, LIMITED BIOAVAILABILITY, RAPID DEGRADATION, AND RELIANCE ON SYNTHETIC MATERIALS, WHICH REDUCES EFFECTIVENESS. THIS TECHNOLOGY PROTECTS SENSITIVE BIOACTIVE MOLECULES, ENHANCES FORMULATION STABILITY, AND ENABLES CONTROLLED RELEASE, IMPROVING PRODUCT PERFORMANCE. THE TECHNOLOGY HAS APPLICATION IN PERSONAL CARE PRODUCTS, PHARMACEUTICALS, NUTRACEUTICALS, AGRICULTURAL, FOOD, AND BIOMEDICAL APPLICATIONS. RESULTS SHOW THAT IT MAY IMPROVE THE STABILITY, DISPERSION, AND CONTROLLED RELEASE OF ULTRAVIOTLET (UV) FILTERS FOR SUNSCREEN AND PERSONAL CARE FORMULATIONS. THIS I-CORPS PROJECT UTILIZES EXPERIENTIAL LEARNING COUPLED WITH FIRST-HAND INVESTIGATION OF THE INDUSTRY ECOSYSTEM TO ASSESS THE TRANSLATION POTENTIAL OF A NANOCARRIER PLATFORM ENGINEERED FOR THE ENCAPSULATION, STABILIZATION, AND CONTROLLED RELEASE OF BIOACTIVE MOLECULES. EXISTING DELIVERY SYSTEMS OFTEN ADDRESS ONLY ONE LIMITATION, SUCH AS STABILITY OR DISPERSION. THIS TECHNOLOGY IS BIODEGRADABLE AND USES NATURALLY PLANT-DERIVED LIPID NANOSTRUCTURED CARRIERS TO IMPROVE ENCAPSULATION EFFICIENCY, BIOAVAILABILITY, RELEASE KINETICS, AND PROTECTION OF SENSITIVE COMPOUNDS. IT IS DESIGNED AS A MODULAR PLATFORM THAT CAN BE ADAPTED TO DIFFERENT BIOACTIVE COMPOUNDS AND HAS POTENTIAL APPLICATIONS IN SUNSCREEN AND PERSONAL CARE, COSMETICS, DERMATOLOGY, AGRICULTURE, BIOTECHNOLOGY, AND OTHER HEALTHCARE PRODUCTS. THE INITIAL FOCUS IS USE IN SUNSCREEN AND PERSONAL CARE, WHERE CHALLENGES RELATED TO ACTIVE INGREDIENT STABILITY, PHOTODEGRADATION, DISPERSION, AND FORMULATION COMPATIBILITY REPRESENT SIGNIFICANT INDUSTRY NEEDS. THIS APPROACH MAY REDUCE FORMULATION COMPLEXITY, ENHANCES PRODUCT PERFORMANCE, AND EXTENDS THE FUNCTIONAL LIFESPAN OF BIOACTIVE MOLECULES WHILE MAINTAINING COMPATIBILITY WITH BIODEGRADABLE MATERIALS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $50.0k | 8/14/26 |