I-corps: translation potential of a plant-derived nanocarrier platform for improving the stability, dispersion, and controlled delivery of bioactive compounds

Active Project Grant Awarded Last action

Award ID
2638478
Recipient
Awarding agency
Obligated
$50,000

Award facts

Assistance listing
47.084 NSF Technology, Innovation, and Partnerships
Completion date 14% complete
Place of performance
College Station, TX 77843, USA

Award details come from USAspending.gov.

Description

Abstract
This i-corps project is based on the development of a nanosized transport system using plant materials to stabilize and deliver active substances such as drugs. Current delivery systems often suffer from poor stability, limited bioavailability, rapid degradation, and reliance on synthetic materials, which reduces effectiveness. This technology protects sensitive bioactive molecules, enhances formulation stability, and enables controlled release, improving product performance. The technology has application in personal care products, pharmaceuticals, nutraceuticals, agricultural, food, and biomedical applications. Results show that IT may improve the stability, dispersion, and controlled release of ultraviotlet (UV) filters for sunscreen and personal care formulations. This i-corps project utilizes experiential learning coupled with first-hand investigation of the industry ecosystem to assess the translation potential of a nanocarrier platform engineered for the encapsulation, stabilization, and controlled release of bioactive molecules. Existing delivery systems often address only one limitation, such as stability or dispersion. This technology is biodegradable and uses naturally plant-derived lipid nanostructured carriers to improve encapsulation efficiency, bioavailability, release kinetics, and protection of sensitive compounds. IT is designed as a modular platform that can be adapted to different bioactive compounds and has potential applications in sunscreen and personal care, cosmetics, dermatology, agriculture, biotechnology, and other healthcare products. The initial focus is use in sunscreen and personal care, where challenges related to active ingredient stability, photodegradation, dispersion, and formulation compatibility represent significant industry needs. This approach may reduce formulation complexity, enhances product performance, and extends the functional lifespan of bioactive molecules while maintaining compatibility with biodegradable materials. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.- subawards are not planned for this award.

Quick answers

Who received award 2638478?

2638478 was awarded to Texas A&M Agrilife Research by National Science Foundation on September 1, 2026.

How much is award 2638478 worth?

$50,000 has been obligated on 2638478.

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