Project Grant 2625576
- The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded $200,000 to the University of Houston on October 1, 2026, for collaborative research developing FBEP-enabled electrochemical sensors for heart failure monitoring under the Engineering program (CFDA 47.041). The research develops a wearable sensing approach for continuous monitoring of N-terminal pro-B-type natriuretic peptide in skin interstitial fluid as an alternative to intermittent blood draws...
- The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded the University of Kansas Center For Research Inc. $200,000 on October 1, 2026, under the Engineering program (CFDA 47.041) to develop electrochemical sensors for continuous heart failure monitoring. The research will engineer an aptamer-based electrochemical platform combining molecular-recognition engineering, electrically controlled sensing using fast biphasic electric pulse waveforms, and wearable...
- The National Science Foundation (NSF) awarded a three-year, $449,999 Project Grant under their Engineering program (CFDA 47.041) to the University of Cincinnati to develop an implantable biosensor platform that can continuously monitor various biomarkers in the body for over a year. The project aims to create a new class of long-lasting aptamer-based sensors protected by robust porous oxide coatings, which would enable the first practical implantable monitoring system for managing chronic...
- The National Science Foundation awarded the University of Connecticut $358,371 on October 1, 2025, under the Engineering program (CFDA 47.041) to develop a wireless bioelectronic system for monitoring fentanyl in the brain of small animal models. The project focuses on three technical objectives: isolating, characterizing, and engineering aptamers targeting fentanyl; developing an implantable nanoporous electrochemical aptamer-based (NANOEAB) fentanyl sensor with improved in vivo longevity...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Cincinnati Sponsored Research Services Division $398,400 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop chemically-modified aptamer electrochemical sensors for ultra-sensitive biomonitoring. The research advances continuous biochemical monitoring technology to detect biomarkers at picomolar-to-nanomolar...
- This Project Grant award for $299,712 from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports the development of electrochemical aptamer-based (E-AB) sensors for the rapid and accurate detection of multiple cardiovascular disease (CVD) biomarkers. The University of South Carolina, with mentorship from collaborators at the University of Cincinnati, will design and characterize these multiplexed E-AB sensors to enable early diagnosis of CVDs, which are...
- The National Science Foundation (NSF) awarded a $550,000 Project Grant under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) to the University of Missouri System to develop six-lead, wearable heart monitors using innovative, multifunctional, porous, soft materials. The project aims to enhance wearable heart monitors for improved cardiac health management by addressing current limitations in ambulatory ECG monitoring, such as motion-induced artifacts and limited...
- This $200,000 Project Grant awarded by the National Science Foundation (NSF) Division of Electrical, Communications and Cyber Systems under CFDA 47.041 (Engineering) aims to develop and implement a novel testing platform to evaluate the accuracy of wearable photoplethysmography-based blood pressure monitoring devices. The University of Maryland, College Park will construct a bench flow phantom that simulates physiologically relevant blood pressure, blood flow, anatomical, and optical...
- The National Science Foundation awarded $304,950 to Senphonix, Inc. on October 1, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop injection-molded biosymbiotic devices for long-term, multimodal physiological monitoring as a Small Business Technology Transfer (STTR) Phase I project. The work centers on designing and demonstrating a lightweight mesh wearable sleeve with embedded microsensors, coupled with wireless charging electronics, remote radio...
- The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $450,000 Project Grant to the Texas A&M Engineering Experiment Station (Tees) to develop an injectable, grain-of-rice size glucose biosensor for continuous blood sugar monitoring. The key products or services to be provided under this 3-year grant include: Developing an injectable glucose biosensor comprised of a self-cleaning membrane and a near-infrared fluorescence...
The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded the University of Connecticut $200,000 on October 1, 2026, under the Engineering program (CFDA 47.041) to develop wearable electrochemical sensors for continuous heart failure monitoring. The project will create an aptamer-based electrochemical platform combining molecular-recognition engineering, electrically controlled sensing, and wearable microneedle technology to measure N-terminal pro-B-type natriuretic peptide (NT-proBNP) in skin interstitial fluid. Current heart failure diagnostics rely on intermittent blood draws that provide only isolated snapshots; more frequent NT-proBNP measurements could reveal rising, falling, or rebound trajectories and support earlier recognition of worsening disease or treatment response. The research has three interdependent objectives: develop and optimize NT-proBNP-binding aptamers with high affinity, selectivity, and stability in biofluids at physiological temperature; determine how fast biphasic electric pulse waveform parameters and electrochemical readout conditions control signal generation, interface recovery, and sensing bandwidth; and establish principles for continuous protein biomarker monitoring broadly applicable beyond this specific biomarker. The project runs from October 1, 2026, through September 30, 2029, with performance at Storrs, Connecticut. Educational outcomes include integration of project concepts and results into undergraduate and graduate course modules and outreach activities on wearable biosensors and heart-health monitoring.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $200.0k | 8/5/26 |