Project Grant 2548668
- Federal Grant Award Summary Ball State University received a $370,817 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041) effective September 1, 2025, through August 31, 2028. The award funds research and development of heterostructured bismuth-based metal oxide photocatalysts designed to degrade chlorinated organic contaminants, including common groundwater pollutants such...
- This three-year Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems will support the development of new green-chemical catalysts based on Rieske dioxygenase scaffolds through directed evolution at Ball State University. Totaling $366,434, the award aims to evolve previously uncharacterized dioxygenases found in soil bacteria to expand their substrate ranges for valuable applications in organic synthesis and...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded $494,253 to Indiana University for a Project Grant (CFDA 47.041 - Engineering) beginning April 15, 2025, with completion targeted for March 31, 2028. The award supports structural and biophysical research on evolved Fe(II)/2-ketoglutarate-dependent azidases designed to expand enzymatic C-H (carbon-hydrogen) functionalization capabilities. The core...
- This $485,752 Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) supports collaborative research to develop a data-driven approach to microreaction engineering guided by autonomous robotic experimentation. Key products and services include the creation of an interdisciplinary knowledge framework to accelerate mechanistic reaction studies and synthesis process development for emerging materials and molecules with multi-stage chemistries. Researchers will...
- This National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET) Project Grant of $579,734 awarded to Rutgers, The State University, aims to accelerate the design and development of synthetic enzymes through a combination of artificial intelligence, polymer science, and robotics. The project will implement an iterative design-build-test-learn process to reveal the underlying structure-function relationships that can produce enzyme mimetic...
- Federal Grant Award Summary Arizona State University received a $340,000 Project Grant award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems (Engineering Program, CFDA 47.041) commencing September 1, 2025, and concluding August 31, 2028. The award supports fundamental research to deconvolute the competing effects of amorphous metal catalysts for carbon dioxide electrochemical reduction. The primary deliverable is scientific...
- The National Science Foundation (NSF) awarded a $330,000 Project Grant under the Engineering (CFDA 47.041) program to the Regents of the University of Michigan to conduct collaborative research on engineering catalyst selectivity for the deconstruction and re-synthesis of biomass and waste plastic feedstocks. The research aims to develop a fundamental understanding of how tuning catalyst architecture can enable selective cleavage of carbon-oxygen bonds in multifunctional organic molecules...
- The National Science Foundation (NSF) awarded a $638,566 Project Grant under the Engineering program (CFDA 47.041) to the University of Delaware. The grant supports a collaborative research effort to develop a computational-experimental methodology using machine learning to design stable, active, and selective single-atom catalysts for industrial applications. The project aims to uncover physics-inspired descriptors to predict how the support material properties influence the stability,...
- This two-year, $200,000 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems will fund research at the Long Beach Research Foundation to develop multi-activity proteins for improved carbohydrate deconstruction. Specifically, the Foundation will produce and test 85 engineered multi-activity proteins containing two catalytic domains each. These proteins aim to increase biomass conversion for alternative fuels and...
- The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $388,369 Project Grant to the Regents of the University of Minnesota to support research extending the catalytic activity of enzymes to unnatural reactions from May 15, 2021 through April 30, 2024. Under the grant, the University of Minnesota will conduct research exploring how to engineer enzymes to catalyze reactions not found in nature, with the goal of expanding the...
Ball State University received a $392,649 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), awarded May 1, 2026, with completion targeted for April 30, 2029. The award supports the development of improved aromatic-metabolizing enzymes through generalizable enzyme engineering strategies. Primary deliverables include engineered enzyme variants from three enzyme families—extradiol dioxygenases, aromatic peroxygenases, and ferulic acid decarboxylases—with enhanced reactivity and catalytic efficiency for aromatic compounds used in chemicals, fragrances, and pharmaceuticals. The research employs directed evolution platforms, rational design, and artificial intelligence-based protein modeling to optimize substrate tunnel architecture and enzyme-substrate interactions. The project also delivers significant workforce development products, featuring undergraduate researcher teams conducting experimental and analytical work under a design-test-build-learn cycle methodology. By advancing biocatalytic approaches to aromatic compound synthesis, the research aims to reduce energy consumption and solvent waste in industrial chemical manufacturing while providing participating undergraduate students with hands-on training and technical skills that contribute to the future U.S. biomanufacturing workforce.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $392.6k | 6/2/26 |