Project Grant 2532276
Award Date 9/1/25
Completion Date 8/31/28
Dollars Obligated $525K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Greenville, NC 27858, USA
Similar Awards
- East Carolina University received a $140,677 Project Grant award from the National Science Foundation Division of Chemistry on June 1, 2021 to support research titled "Mechanistic and Structural Approaches for Sulfur Acquisition in the Two-Component FMN-Dependent Monooxygenases" through January 31, 2022. The award was made under the Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national...
- This three-year, $525,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports coordinated mechanistic approaches to desulfonation in two-component FMN monooxygenases. East Carolina University will deliver structural investigations of alkane sulfonate monooxygenase systems through X-ray crystallography and analysis, with the University of Massachusetts Boston performing the crystallography work. Quantum mechanical calculations...
- This Project Grant award for $450,000 was provided by the National Science Foundation (NSF) through the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The funding supports collaborative research by Professors Yisong Guo of Carnegie Mellon University and Wei-Chen Chang of North Carolina State University to investigate a group of four enzymes that utilize a single iron atom and molecular oxygen to catalyze diverse chemical reactions. The goal is to elucidate the...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049) provides $645,000 to North Carolina State University to study the structures and functions of a newly discovered class of enzymes called heme oxygenase-like dimetal oxidases/oxygenases (HDOs). The goal is to determine how structurally similar HDO proteins can catalyze radically different chemical transformations. The research will leverage bioinformatics,...
- The National Science Foundation (NSF) awarded a $197,237 Project Grant to the University of Missouri System, doing business as Missouri University of Science & Technology (Missouri S&T), through the Mathematical and Physical Sciences (MPS) program. The grant is being used by Professor Shelley Minteer at the University of Utah to develop new electroanalytical tools for investigating enzymes, which are critical biological catalysts with applications in biotechnology and catalysis. Key...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) to the University of California, Berkeley provides $780,000 in funding to investigate the molecular mechanisms of oxygen-dependent enzymes and develop synthetic mimics. The key objectives are to study a class of oxygen-dependent decarboxylase enzymes that utilize iron, manganese, or mixed metal active sites. This research aims to elucidate the critical oxygen-activated...
- This $700,000 Project Grant awarded on May 1, 2025 by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports Professor Jeffrey Rudolf at the University of Florida in studying bacterial cytochrome P450 enzymes and their redox partners. The project aims to discover new natural products and understand the molecular interactions between P450 enzymes and their required redox partner proteins. This research will provide valuable training for...
- The National Science Foundation (NSF) Division of Chemistry has awarded a $180,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to support a collaborative research project titled "INTERROGATING CATALYTIC EFFICIENCY THROUGH KINETIC, STRUCTURAL AND SMALL-MOLECULE GUIDED INVESTIGATION OF L-DOPA 2,3-DIOXYGENASES." The grant, with an award date of August 1, 2025 and an ultimate completion date of July 31, 2028, will fund a joint investigation by...
- The National Science Foundation (NSF) awarded a $405,960 Project Grant to Rensselaer Polytechnic Institute (RPI) under the Mathematical and Physical Sciences program (CFDA 47.049) to investigate enzymes from organisms living in deep sea environments. The research aims to understand how these enzymes, known as extracellular deoxyribonucleases (exDNases), have adapted to function under the extreme conditions of high pressure and temperature in the deep ocean biosphere. The work will combine...
- This $597,945 federal Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) program supports research by Tobias W. Giessen at the University of Michigan, Ann Arbor to investigate the structure and function of peptide-modifying enzyme filaments found in bacteria and archaea. The proposed work will generate new insights into the self-assembly and catalytic activity of these filamentous enzymes, which...