Project Grant 2449642
- The National Science Foundation (NSF) Division of Chemistry is providing a $315,000 Project Grant award to Muhlenberg College, Rhodes College, and the State University of New York at Cortland to study the catalytic efficiency of L-DOPA 2,3-dioxygenase enzymes. The 3-year collaborative research project, titled "Interrogating Catalytic Efficiency Through Kinetic, Structural and Small-Molecule Guided Investigation of L-DOPA 2,3-Dioxygenases", will systematically modify the size and...
- This $447,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will support research at Haverford College from December 2022 through February 2026. The research team, led by Dr. Louise Charkoudian, will investigate type II polyketide biosynthetic enzyme assemblies across bacterial species to leverage their capabilities for sustainable chemical production. Undergraduate students will gain research...
- The National Science Foundation (NSF), through its Mathematical and Physical Sciences program (CFDA 47.049), awarded a $600,000 project grant to Professor Neil C. Tomson of the University of Pennsylvania. The 3-year project, starting on September 1, 2025, aims to study how iron-based catalysts can selectively activate and functionalize carbon-carbon sigma bonds under mild conditions. This research will lay the groundwork for future technologies that can produce pharmaceuticals, plastics, and...
- This federal Project Grant award of $600,000.00 was provided by the National Science Foundation (NSF) Division of Chemistry through the Mathematical and Physical Sciences Program (CFDA 47.049). The award will support a project led by Professor Diao of New York University (NYU) to study the design of new bidentate chiral nitrogen-based ligands for use in asymmetric catalysis. This research aims to develop more efficient and environmentally-friendly methods for synthesizing small molecule...
- The National Science Foundation (NSF) Division of Chemistry awarded a $375,000 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to support a collaborative research effort between the University of Michigan and the University of Colorado Boulder. The grant, awarded from July 1, 2024 to June 30, 2027, aims to study the role of surface-bound ligands on metal catalysts in the direct synthesis of hydrogen peroxide, an important industrial chemical. The research team,...
- The National Science Foundation (NSF) Chemical Catalysis program awarded a $560,760 project grant to the University of North Carolina at Chapel Hill (UNC-CH) to study dearomatization reactions catalyzed by transition metal complexes derived from earth-abundant metals such as copper, iron, and nickel. This collaborative research project with the Université Grenoble Alpes in France will advance the understanding of how metal-ligand complex characteristics interface with different reagent...
- This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $131,882 to support collaborative research on electrocatalytic synthesis of heterocycles from biomass-derived furanics via immobilized first-row transition metal catalysts. Professors Yujie Sun of Vanderbilt University and De-En Jiang of the University of California, Riverside will develop electrocatalysts using coordinatively unsaturated...
- The National Science Foundation (NSF) Division of Chemistry awarded a $700,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to support a collaborative research effort focused on developing new approaches to catalysis and electrochemistry for the synthesis of biaryl molecules. Professors Daniel Weix and Shannon Stahl of the University of Wisconsin-Madison, Professor Mohammad Rafiee of the University of Missouri-Kansas City, and Professor Robert Paton of...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049) provides $645,000 to North Carolina State University to study the structures and functions of a newly discovered class of enzymes called heme oxygenase-like dimetal oxidases/oxygenases (HDOs). The goal is to determine how structurally similar HDO proteins can catalyze radically different chemical transformations. The research will leverage bioinformatics,...
- This Project Grant award for $450,000 was provided by the National Science Foundation (NSF) through the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The funding supports collaborative research by Professors Yisong Guo of Carnegie Mellon University and Wei-Chen Chang of North Carolina State University to investigate a group of four enzymes that utilize a single iron atom and molecular oxygen to catalyze diverse chemical reactions. The goal is to elucidate the...
The National Science Foundation (NSF) Division of Chemistry has awarded a $180,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to support a collaborative research project titled "INTERROGATING CATALYTIC EFFICIENCY THROUGH KINETIC, STRUCTURAL AND SMALL-MOLECULE GUIDED INVESTIGATION OF L-DOPA 2,3-DIOXYGENASES." The grant, with an award date of August 1, 2025 and an ultimate completion date of July 31, 2028, will fund a joint investigation by researchers at Muhlenberg College, Rhodes College, and the State University of New York at Cortland. The goal is to study how extradiol dioxygenase enzymes can be used to convert naturally abundant catecholic carbon, a key component of lignin in woody plants, into useful materials and products. The research will systematically explore how changing the size and electronic properties of the carbon sources and mutating the enzyme structures affects the efficiency of these molecular conversions. Undergraduate students will participate in the interdisciplinary research and gain hands-on experience, with elements of the project also integrated into coursework at the participating institutions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $180.0k | 7/25/25 |