This Project Grant from the National Science Foundation's Division of Materials Research provides $306,287 to Purdue University under the Mathematical and Physical Sciences program (CFDA 47.049) from September 1, 2022 to August 31, 2025. The grant supports collaborative research to elucidate the rate-limiting steps in biopolymer dissolution when small molecule additives are present. Graduate and undergraduate students, including underrepresented minorities and women, will investigate how...
The National Science Foundation (NSF) awarded a $513,894 Project Grant under its Mathematical and Physical Sciences program (CFDA 47.049) to Tufts University. This 3-year grant, effective July 1, 2023, supports Professor Clay S. Bennett's research to develop new methods for synthesizing deoxy sugars - an important component of many biologically active natural products. The project aims to expand upon approaches that activate sugar hemiacetals as glycosyl sulfonates or tert-butyldimethylsilyl...
This federal Project Grant award of $496,200 from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a research project led by Professor Li at the University of Mississippi. The project aims to use advanced computational modeling techniques to investigate how N-glycosylation, a process where sugar molecules attach to proteins, regulates the function of ion channels - cellular gatekeepers that control vital physiological processes. By...
This $273,055 Project Grant awarded by the National Science Foundation's (NSF) Division of Materials Research under the Mathematical and Physical Sciences (CFDA 47.049) program supports theoretical and computational research on charge patterning and molecular interactions in polyelectrolyte/particle phase behavior. The research aims to advance understanding of how molecular structure, particle configuration, and charge patterning affect phase separation in complex coacervates formed between...
This three-year $525,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports research into the structure, dynamics, and transport properties of charged macromolecular systems in aqueous solutions. The grantee, University of Massachusetts at Amherst, will investigate the hierarchical organization and non-diffusive dynamics of polyzwitterions, as well as forces controlling coacervate gel composite formation and phase behavior,...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research and education in the fields of computational materials science and soft matter engineering. The $337,337 award to Cornell University aims to predict how polyphilic molecules can assemble into solid-like and liquid-like domains, allowing the material to both absorb large strains and self-heal. The project will use molecular dynamics simulations to...
This $243,319 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports research by the University of Florida to characterize protein-polymer conjugates at the atomic level. The goal is to develop a deeper understanding of how polymers can effectively stabilize proteins against denaturation, enabling the design of novel protein-based materials and therapeutics. The research will use NMR spectroscopy to determine the...
The National Science Foundation awarded a $575,000 Project Grant to the University of Colorado Boulder under the Mathematical and Physical Sciences program (CFDA 47.049) from July 1, 2023 to June 30, 2026. The grant funds fundamental research on the development of new stereoselective synthesis methods for challenging carbohydrate and glycomimetic systems of biomedical significance. Principal Investigator Maciej Walczak and his team will focus on cross-coupling reactions using stereodefined...
This $543,251 federal Project Grant award, provided by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049), supports research by Professor Jessica Kramer at the University of Utah to develop chemically tunable models of the cellular glycocalyx. The glycocalyx is a protein and sugar coating on cell surfaces that plays crucial biological roles, particularly in mucin-rich regions like the eyes, lungs, and gastrointestinal...
Professor Amit Basu of Brown University will receive $450,000 through a three-year Project Grant from the National Science Foundation's Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049). The grant will support research to better characterize carbohydrate-carbohydrate interactions at the molecular and supramolecular levels using nuclear magnetic resonance spectroscopy and isothermal titration calorimetry. Specifically, the project aims to identify structural...