This $300,000 project grant from the National Science Foundation will fund research at Cornell University from October 1, 2022 to September 30, 2025. The award is provided through NSF's Engineering Biology and Health Cluster within the Directorate for Engineering, Biological Sciences and Biotechnology, under the CFDA program for Engineering. Specifically, researchers at Cornell University and Washington State University will work to develop new tissue engineering strategies for cartilage repair....
This three-year, $1.2 million project grant from the National Science Foundation's Engineering program (CFDA 47.041) will support research at Washington State University and Cornell University to develop new tissue engineering strategies for cartilage regeneration. The researchers aim to stimulate adult stem cells to become mature chondrocytes for cartilage production through small molecules that interfere with bone cell differentiation genes. Real-time imaging will monitor cell growth...
This $500,000 project grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation supports research titled "GOALI/COLLABORATIVE RESEARCH: INSTABILITIES AND LOCAL STRAINS IN ENGINEERED CARTILAGE SCAFFOLD" being conducted at Cornell University from January 1, 2022 to December 31, 2024. The research aims to improve understanding of instabilities and local strains in engineered cartilage scaffolds, with the goal of enabling innovation in cartilage...
The National Science Foundation awarded a $399,685 project grant to the University of California Irvine under the Engineering program (CFDA 47.041) to develop innovative cartilage tissue engineering strategies utilizing the microgravity environment of the International Space Station. The objectives of the three-year award beginning September 1, 2022 include employing microgravity conditions to enhance key processes in earth-based cartilage tissue engineering such as redifferentiation of expanded...
The National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation awarded The Johns Hopkins University a $324,511 Project Grant under the Engineering federal grant program (CFDA 47.041) for research titled "GOALI/COLLABORATIVE RESEARCH: INSTABILITIES AND LOCAL STRAINS IN ENGINEERED CARTILAGE SCAFFOLD." The two-year award beginning January 1, 2022 will support research into instabilities and local strains in engineered cartilage scaffolds to better understand...
The National Science Foundation (NSF) has awarded a 5-year, $182,664 CAREER grant (CFDA 47.041 - Engineering program) to the Marshall University Research Corporation (MURC) to explore the use of electrospinning and electrospraying techniques for differentiating human adipose-derived stem cells into chondrocytes. The overarching goal is to develop an innovative and personalized approach to generate chondrocytes, or cartilage cells, that can be used for regenerative medicine applications focused...
The National Science Foundation (NSF) awarded a $1,000,000 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Impressio Inc., a for-profit manufacturer headquartered in Thornton, Colorado. The award supports the development, verification, validation, and commercialization of a liquid-crystal elastomer (LCE)-based cartilage replacement device to treat hallux rigidus, a joint disorder affecting the base of the big toe. The project aims to...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award provides $305,000 to Novaurum Biosciences Incorporated to develop a novel mammalian cell-based nano-biological coating for implantable medical devices. The project aims to address the critical issue of implant-related infections, which cost the U.S. healthcare system over $8.6 billion annually. The proposed nano-biological coating is designed to inhibit biofilm formation and...
This $962,735 cooperative agreement from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships program (CFDA 47.084) supports the development of an enhanced biodegradable tissue adhesive for gastrointestinal surgical wound closure applications by Bezwada Biomedical LLC. The small business will refine a polyurethane-based adhesive formulation and assess its in vivo performance to identify a safe, easy-to-use lead tissue adhesive that can help prevent anastomotic...
This National Science Foundation (NSF) Engineering (CFDA 47.041) project grant supports research to study the relationship between microscopic structure and macroscopic function of articular cartilage under loading conditions. The $624,622 award to the University of Vermont will investigate how quantitative magnetic resonance imaging (MRI) metrics of cartilage microstructure, biomechanical testing, and computational modeling can improve the understanding of cartilage response to loading and...