Project Grant 2028008

This $1 million cooperative agreement from the National Science Foundation's Technology, Innovation, and Partnerships program aims to develop a microbial discovery and biosynthesis platform for targeted protease inhibitors to treat COVID-19. Think Bioscience, Inc. will expand its demonstrated approach using microbial systems to guide the discovery and assembly of protease inhibitors. The company will generate new intellectual property covering the discovery platform and promising small molecules...

Intelligent Medicine Inc. received a $275,842 National Science Foundation Project Grant to develop a cloud-based simulation platform for modeling airborne infectious disease spread. Funded through NSF's Technology, Innovation, and Partnerships program (CFDA 47.084), the project advances a hybrid computational approach utilizing multi-scale fluid analysis to enable faster-than-real-time simulation of viral particle dispersion and surface contamination in indoor environments. This will allow...

This Project Grant award from the National Science Foundation's Division of Computing and Communication Foundations supports the development of computational tools and frameworks for bio-social modeling of future pandemics through Arizona State University's PIPP PHASE I: Computational Foundations for Bio-Social Modeling of Unseen Pandemics project. Funded under the Computer and Information Science and Engineering federal grant program (CFDA 47.070), the $807,531 award will advance predictive...

This $2 million project grant from the National Science Foundation's Division of Computing and Communication Foundations supports the development of predictive modeling tools to aid pandemic prevention and response efforts. Funded under the Computer and Information Science and Engineering program, the 18-month award to Boston Children's Hospital will plan a future center-scale effort to address gaps in understanding and modeling pandemic potential, impact of interventions, and factors...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) provides $382,852 to Brown University to develop methodological innovations for improving the use of observational causal inference models to estimate the population-level impact of interventions on infectious disease outcomes. The key products and services to be delivered include: Proposing robust specifications for observational...

This $968,765 Project Grant awarded by the National Science Foundation's (NSF) Division of Mathematical Sciences (CFDA 47.049 - Mathematical and Physical Sciences) will develop a flexible modeling framework to simulate the impact of various testing-based infection control strategies for respiratory pathogens like SARS-CoV-2. The project aims to improve our ability to control existing respiratory diseases and enhance preparedness for future pandemics. Key deliverables include: Developing a...

The National Science Foundation (NSF) awarded a $200,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of Virginia to develop data-driven, multimodal methods for behavior-based epidemiological modeling. The key objectives are to: Improve techniques for deriving meaningful insights from imperfect, real-world sensor data like mobile phones and search engine logs to capture complex human behaviors in real-time. Couple agent-based disease models...

The National Science Foundation awarded a $195,381 Project Grant to Washington State University under the Biological Sciences program (CFDA 47.074) for the period of February 1, 2021 through January 31, 2024. The grant aims to fund the RAPID project "Curtailing Nosocomial Amplification of COVID-19," which seeks to develop epidemiological models to better understand and mitigate the transmission of COVID-19 in healthcare settings. As part of the grant, Research Triangle Institute will...

This $1,000,000 Cooperative Agreement awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports research and development efforts by Akanocure Pharmaceuticals Inc. to optimize a novel, broad-spectrum antiviral and immunomodulatory agent for oral administration against coronaviruses. The project focuses on lead optimization, including the design, synthesis, and testing of analogs with improved drug-like properties for...

The National Science Foundation Division of Industrial Innovation awarded a $255,908 Project Grant to Verisim Life, Inc. under the Engineering (47.041) federal grant program. The grant supports Verisim Life's efforts to rapidly repurpose and translate COVID-19 therapeutics using an AI-based biosimulation platform. Specifically, the company will apply its platform to research multi-target therapies involving angiotensin-converting enzyme 2 and calcium pathways, which could help combat the...