Project Grant 2027482

This federal Project Grant award from the National Center for Advancing Translational Sciences (NCATS), CFDA #93.350, aims to develop a consensus-driven measurement strategy for assessing cognitive function in patients with thrombotic thrombocytopenic purpura (TTP), a rare and life-threatening blood disorder. The $456,348 award to Duke University, scheduled to be completed by July 31, 2026, will fund a study to determine the impacts of TTP on cognitive function and establish a rigorous...

This federal Project Grant award of $545,983 from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395) supports research to identify molecular regulators of interactions between circulating tumor cells (CTCs) and the host immune system, with a focus on triple-negative breast cancer (TNBC). The overarching goal is to understand how CTC clusters form and interact with immune cells, in order to develop new therapeutic approaches to block CTC-mediated...

This Project Grant award from the National Cancer Institute's Cancer Treatment Research program (CFDA 93.395) provides $159,574 to the University of Kansas Medical Center Research Institute, Inc. (KUMCRI) to increase access and participation to early phase clinical trials for underrepresented populations, including veterans. The project aims to develop sustainable strategies to extend access and boost participation in the Experimental Therapeutics Clinical Trials Network (ETCTN) clinical...

The Uniformed Services University (USU) and University of California San Francisco (UCSF) have been awarded a $53,268,006 Cooperative Agreement by the Uniformed Services University of Health Sciences under the Uniformed Services University Medical Research Projects program (CFDA 12.750). This 2-year award, effective September 1, 2024, supports a partnership focused on developing therapeutics for Chronic Traumatic Encephalopathy (CTE). Key objectives include: Dr. Pruisner at UCSF will develop...

The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $312,000 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to the Regents of the University of Michigan Office of Research and Sponsored Projects to establish the Michigan Collaborative Hub for TMD Patient-Centric Research (MICH T PCR). The goal of the award is to transform the treatment of temporomandibular disorders (TMDs) through the translation of clinically-relevant innovations. The...

The federal Cooperative Agreement award of $1,105,466.00 was granted by the National Center for Advancing Translational Sciences (NCATS) on August 1, 2024 to The Research Foundation For The State University Of New York (RF SUNY). The purpose of this award, under CFDA program 93.350, is to conduct a series of 3 randomized controlled trials (RCTs) evaluating the impact of remote versus in-person clinical trial methods on key trial efficiency and quality outcomes, such as participant accrual,...

The National Center for Advancing Translational Sciences (NCATS) awarded a $429,000 Project Grant (CFDA 93.350) to The Regents of the University of Colorado (University of Colorado-Denver) to address critical gaps in enabling clinical trial readiness for the rare Posterior Cortical Atrophy (PCA) syndrome. Over a 2-year period from August 2024 to July 2026, the project aims to longitudinally assess patient-reported and informant-reported PCA-specific clinical outcome assessments (COAs),...

The Regents of the University of Colorado, doing business as the University of Colorado-Denver, received a $451,938 Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) on September 22, 2023. The funding supports the establishment of the "Pediatric Autoimmune Consortium for Exposome Research (PACER)," a new transdisciplinary research team focused on developing the infrastructure needed for a future large-scale study on the...

This Project Grant award from the National Cancer Institute's Cancer Research Manpower (CFDA 93.398) program provides $167,584 to the University of California, San Diego (UCSD) to generate and study induced pluripotent stem cell (iPSC)-derived atypical teratoid rhabdoid tumor (ATRT) models. The goal is to investigate the cell of origin and identify therapeutic vulnerabilities for this aggressive pediatric brain cancer. Key project activities include: Performing RNA sequencing analyses on...

This federal Cooperative Agreement award of $17,134,164 from the National Center for Advancing Translational Sciences (NCATS), CFDA 93.350, will establish the Consortium for Translational and Precision Health (CTPH) led by Baylor College of Medicine and the University of Houston. The CTPH will serve as a hub to advance clinical translational science, precision health, and health equity through new technologies, research methods, community engagement, and workforce development. Key objectives...