Project Grant 1940395

Micropure Genomics Inc. received a $274,199 Project Grant award from the National Science Foundation to advance methods for rapid, end-to-end sample preparation for sequencing applications. Under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the company will develop an automated process relying on electro-hydrodynamic trapping to isolate genomic material like DNA or RNA from cells in a flow cartridge. The process aims to significantly reduce preparation time while...

This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $350,000 to develop a microfluidic/nanofluidic sample preparation platform to improve protein extraction, purification, and analysis for single-cell and low-input proteomics. The new platform aims to enhance the efficiency and reliability of protein extraction and denaturation, enabling more comprehensive proteome...

This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program (CFDA 47.084) provides $275,000 to Dcan Biosciences LLC to develop an advanced microfluidic system for cancer diagnosis and monitoring. The system aims to isolate and assess circulating tumor cells (CTCs) and CTC clusters (CTCCs) from patient blood samples to enable highly sensitive and accurate liquid biopsies. Key objectives include designing a hybrid microfluidic device for...

This $275,000 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program supports the development of a label-free, high-resolution, high-throughput protein screening platform called Vibrational Spectroscopy with Metasurface Optics (VISMO). The technology aims to enable simultaneous, minute-scale measurement of millions of protein samples, which would dramatically improve the lengthy and costly cycles...

Partillion Bioscience Corp. was awarded a $659,037 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences to develop reagent products enabling high-throughput screening and selection of single cells based on secreted bio-products. Under the Biomedical Research and Research Training program (CFDA 93.859), Partillion plans to transition its lab-on-a-particle technology—highlighted as a 2020 SLAS Innovation Award winner—into the first reagent product...

The National Science Foundation awarded Cytorecovery Inc. a $255,986 Small Business Technology Transfer Phase I Project Grant under the Engineering program (CFDA 47.041) on March 15, 2021. The grant funded the development of on-chip integration of sample preparation and monitoring capabilities with dielectrophoretic cell isolation techniques. The Engineering program seeks to improve quality of life and economic strength by fostering innovation and excellence in engineering research. This award...

The National Science Foundation awarded a $275,000 Project Grant to Oraliva, Inc. under the Technology, Innovation, and Partnerships program to develop a portable, programmable single cell cytology platform for the early detection of epithelial cancers. The platform will combine microfluidics and artificial intelligence to classify potentially cancerous tissue in near real-time through multiparameter single-cell analysis and automated evaluation. The objectives are to link different clinical...

This $256,000 National Science Foundation Project Grant under the NSF Technology, Innovation, and Partnerships program will support the development of a universal connector for high-density microfluidic chip interfaces by Neptune Fluid Flow Systems LLC. The proposed connector aims to advance lab-on-a-chip and other life science platforms by introducing a standardized microfluidic chip interface. This new interface seeks to dramatically increase diagnostic testing speeds for doctors and medical...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I SBIR award provides $295,000 to Tanda Biotech Corporation to validate an innovative filter flow channel design for tubular membrane filters used in large-scale bioproduction. The project aims to enhance resource efficiency, expedite cleaning and regeneration processes, and significantly boost filtration system capacities by one or two orders of magnitude. The advancements are expected to...

This Project Grant award, provided by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop a microchip-based technology for advanced cell engineering. The $305,000 award to Cellecho, Inc., with a performance period from April 2025 to March 2026, will fund the design and optimization of an instrument that leverages sound waves and electric fields to efficiently modify cells with high throughput. The broader goal is...