Project Grant 1648053

Federal Grant Award Summary: SPINSEQ Project Electronic Biosciences, Inc. received a Phase I Small Business Innovation Research (SBIR) Project Grant of $383,482 from the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172), awarded on June 6, 2025, with a completion date of May 31, 2027. The company is developing SPINSEQ, an innovative RNA sequencing platform designed to deliver precise and accurate transcriptomic analysis while preserving RNA...

Molecular Intelligence LLC received a $435,882 Phase I Small Business Innovation Research (SBIR) Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 1, 2025, with completion targeted for February 28, 2027. The company will develop advanced artificial intelligence-enabled software tools for structure and ligand modeling capable of accurately modeling drug-receptor interactions...

Electronic Biosciences, Inc. received a $350,000 Phase I Small Business Technology Transfer (STTR) project grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded on June 1, 2025, with a completion date of May 31, 2027. The company, in collaboration with Distinguished Professor Cynthia J. Burrows, is developing the first high-accuracy sequencing technology capable of simultaneously detecting...

The National Science Foundation (NSF) awarded a $299,916 EAGER (Early-concept Grants for Exploratory Research) grant under the Biological Sciences program (CFDA 47.074) to The Johns Hopkins University to develop EVIANN, a novel genome annotation software for plant genomes. The project aims to create an open-source software package that relies on experimental evidence rather than ab initio gene finding techniques to more accurately locate functional elements on plant genomes. Specifically, the...

This $275,000 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program supports the development of a label-free, high-resolution, high-throughput protein screening platform called Vibrational Spectroscopy with Metasurface Optics (VISMO). The technology aims to enable simultaneous, minute-scale measurement of millions of protein samples, which would dramatically improve the lengthy and costly cycles...

This $2,963,428 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) aims to develop critical infrastructure and tools for interpreting genomic data. The project will create high-quality genome assembly workflows, comprehensive documentation, and interactive training materials to make these advanced genomic analysis capabilities accessible to a wide audience of biology researchers. This will enable downstream discoveries in areas such as...

The U.S. National Science Foundation (NSF) awarded a $303,864 Phase I Small Business Innovation Research (SBIR) grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Core Biotherapeutics, Inc. (UEI N9FGZ15RQGJ4) located in Ladera Ranch, CA. The project aims to develop a platform for discovering therapeutic drug candidates that can modulate molecular networks driving diseases, with the potential to produce disease-modifying effects for neurodegenerative...

This three-year Project Grant from the National Science Foundation's Division of Information and Intelligent Systems under the Computer and Information Science and Engineering program ($600,000) will support the development of new computational methods and software for analyzing collections of genomic variants. Specifically, the grantee, Carnegie Mellon University, will create algorithms and open-source software tools to more accurately construct, compare, and assess the complexity of genome...

This SBIR Phase I award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Caravel Bio, Inc. to develop a novel synthetic biology platform for high-throughput directed evolution of spore-displayed enzymes. The project aims to create customizable enzyme solutions for industrial biocatalyst applications by improving key properties like enzyme activity, stability, and loading density. The technology uses a...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will support the development of two digital applications to provide immediate feedback and assessment for student-folded protein models using 3D Molecular Designs' Mini-Toobers modeling tool. The $591,842 award will fund the creation of a Student Training App that uses augmented reality to give students real-time feedback on modeling alpha...