Project Grant 1646677

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) award provides $275,000 to Lensguide Imaging Technology Inc. to develop a miniaturized, 100 μm diameter optical imaging microendoscope for in vivo deep tissue imaging up to 3 mm depth with subcellular resolution. The product will enable researchers to visualize biological dynamics in live animals beyond the superficial tissue layers, facilitating new discoveries across biomedical fields. This SBIR Phase...

This SBIR Phase I Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) provides $305,000 to Coherent Photonics, LLC to develop innovative metasurface optical waveguiding devices (MOWGs). The goal is to create compact, lightweight, and cost-effective optical systems that can replace traditional assemblies of optical components like lenses and mirrors. The novel metasurface-based waveguides will enable subwavelength-level control...

This $275,000 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program supports the development of a label-free, high-resolution, high-throughput protein screening platform called Vibrational Spectroscopy with Metasurface Optics (VISMO). The technology aims to enable simultaneous, minute-scale measurement of millions of protein samples, which would dramatically improve the lengthy and costly cycles...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will fund the development and validation of a novel class of scanning probe microscopy (SPM) probes for rapid identification of infectious disease agents. The $295,308 award to Actoprobe LLC aims to dramatically increase the sensitivity and spatial resolution of scanning...

This federal Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $305,000 to Nanores LLC, a for-profit small business, to develop a compact, multi-color super-resolution imaging system capable of visualizing biological tissues at nanoscale precision. The project aims to overcome limitations of existing imaging technologies by incorporating advanced features like adaptive optics and spinning disk technology...

This STTR Phase I grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program supports the development of a compact, multi-wavelength interferometric system for real-time, in-situ metrology in high-precision optical manufacturing. The $274,524 project aims to deliver a market-ready, on-machine metrology system that can improve efficiency and accuracy in diamond tool alignment, surface metrology, and overall manufacturing throughput by...

The National Institute of General Medical Sciences (NIGMS) awarded a $1,935,256 Project Grant (CFDA 93.859) to Photothermal Spectroscopy Corp. to develop and commercialize a Video Rate Photothermal Infrared (VR-PTIR) imaging and spectroscopy system. The VR-PTIR technology will provide 10-30x better spatial resolution than conventional infrared spectroscopy and operate up to 1000x faster than previous photothermal infrared microscope systems. This advanced spectroscopy platform has potential...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Small Business Innovation Research (SBIR) Phase I project award of $274,998 to Magnify Biosciences Inc. aims to develop an automated "AutoMagnify" device that physically expands biological specimens up to 1,000 times in 3D while preserving spatial and molecular integrity. This advancement will enable conventional light microscopes to achieve nanoscale imaging resolution capabilities...

This $769,749 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences will support the development of Fluorescence Enhanced Photothermal Infrared Spectroscopy (FE-PTIR) technology by Photothermal Spectroscopy Corp. The FE-PTIR technique aims to provide simultaneous fluorescence microscopy and sub-micron infrared spectroscopy to map the distribution of fluorescently labeled biomolecules within cells and tissues while also analyzing their chemical...

The National Science Foundation awarded Pensievision, Inc. $255,947 under the Technology, Innovation, and Partnerships program (CFDA 47.084) to develop an endoscopic 3D imaging system for evaluating cancers and disorders of the esophagus and pharynx. The Small Business Innovation Research Phase I project will combine liquid lens technology, artificial intelligence software, and astronomical imaging techniques to generate three-dimensional images of early-stage esophageal and throat tumors....