The State of Alaska Department of Health has been awarded a $6,999,999 Project Grant from the U.S. Department of Justice's Bureau of Justice Assistance under the Comprehensive Opioid, Stimulant, and other Substances Use Program (CFDA 16.838). The grant will fund a 3-year initiative to improve Alaska's statewide infrastructure for overdose fatality reviews, support regional activities to address substance use disorders across the state's diverse communities, and strengthen partnerships with first responders and corrections agencies through naloxone distribution and post-overdose outreach. Key activities include enhancing overdose fatality reviews, providing targeted funding to Alaska's seven public health regions, and expanding naloxone access for first responders and justice-involved individuals. The goal is to reduce overdose deaths, improve public health practices, and strengthen state, tribal, and community partnerships in addressing substance use challenges across Alaska.