Project Grant 0810794

This National Science Foundation (NSF) Cooperative Agreement award, funded under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, supports the development of a novel, miniaturized ion trap mass spectrometer technology by Ionicscale LLC, a small technology company. The $1,000,000 project aims to create an ultra-compact, remotely programmable chemical analyzer that can greatly expand the accessibility and affordability of mass spectrometry-based chemical detection and...

The National Science Foundation awarded Ionicscale LLC $256,000 under the Technology, Innovation, and Partnerships federal grant program to develop low-cost, portable mass spectrometers based on a chip-scale ion trap mass analyzer. The award aims to advance the company's technology for ubiquitous, high-specificity chemical analysis through a novel ion trap geometry that can be microfabricated at lower costs. This has the potential to bring mass spectrometry capabilities, which are currently...

This National Science Foundation Project Grant of $255,261 awarded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) will fund the development of optimized extraction and projection optics for ion point sources. Steam Instruments Inc. will demonstrate technology advances in imaging mass spectrometry through this Small Business Innovation Research Phase I project. Specifically, the company aims to markedly improve mass resolving power to separate key mass...

This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program totaling $256,000 will fund the development of an optimized ion mobility spectrometry system for distributed chemical sensing without the use of radioactive ionization sources. The awardee, Sensit Ventures Inc. of Davis, California, will establish an experimental and theoretical framework to miniaturize differential mobility spectrometry technology for analytical-quality chemical...

This National Science Foundation Technology, Innovation, and Partnerships Project Grant of $256,000 will support the development of a novel mass spectrometer by Moires Instruments, LLC to identify molecular isomers and distinguish their conformational forms. The instrument uses high electric fields to manipulate neutral molecules based on their dipole moments, separating them by mass-to-dipole-moment ratio rather than conventional mass-to-charge ratio. This approach aims to reduce the...

The National Science Foundation awarded a $877,600 project grant under the Mathematical and Physical Sciences program (CFDA 47.049) to The Research Foundation for the State University of New York on behalf of Dr. Steven Ray at the State University of New York at Buffalo. The grant supports development of microwave-enhanced ionization techniques to improve capabilities for mass spectrometry, an important chemical analysis tool. Dr. Ray and his research team will work to refine ionization...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to advance the field of native mass spectrometry (MS) analysis. The $316,825 award to Massmatrix Inc., effective May 1, 2025 through April 30, 2026, will fund the development of an innovative intact mass deconvolution method to significantly improve the speed, accuracy, and user-friendliness of protein and nucleic acid molecular...

The National Science Foundation Office of Integrative Activities awarded a $1,179,143 Project Grant to the University of New Hampshire (UNH) to acquire an Orbitrap Eclipse Tribrid mass spectrometer. This equipment will (i) dramatically improve UNH's mass spectrometry capabilities to expedite diverse research projects, (ii) facilitate hands-on training and inquiry-based learning on modern instrumentation, and (iii) establish a regional high-resolution mass spectrometry facility. The funding...

This National Science Foundation project grant of $237,745 awarded on September 1, 2022 through August 31, 2025 under the Mathematical and Physical Sciences program (CFDA 47.049) will support the development of a variable temperature ion trap mass spectrometer at Stony Brook University. The mass spectrometer will facilitate isomer-selective thermochemical, structural, and spectroscopic characterization of bimolecular interactions to advance research in biochemistry, medicinal chemistry,...

This $275,000 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program supports the development of a label-free, high-resolution, high-throughput protein screening platform called Vibrational Spectroscopy with Metasurface Optics (VISMO). The technology aims to enable simultaneous, minute-scale measurement of millions of protein samples, which would dramatically improve the lengthy and costly cycles...