Project Grant 047906474

Federal Grant Award Summary Toro Bio, Inc. received a $304,870 Phase I Small Business Innovation Research (SBIR) award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) effective October 1, 2025 through September 30, 2026. The company will develop an automated, single-use bioreactor system designed to manufacture tumor-infiltrating lymphocyte (TIL) cell therapies at the point of care. The system aims to decentralize cell therapy...

Federal Project Grant Award Summary Z Biotech, LLC received a $306,782 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 1, 2025, with completion targeted for August 31, 2026. This Phase I award supports continued development and commercialization of sialoglycan-recognizing probes (SGRPs)—engineered molecular tools derived from naturally evolved microbial molecules such as...

The National Institute of Standards and Technology awarded Zymosense Inc. a $800,000 Cooperative Agreement under the Science, Technology, Business and/or Education Outreach federal grant program (CFDA 11.620) for the period of September 1, 2022 through August 31, 2024. Under this award, Zymosense will optimize its automated pipetting screening tool for assessing single-walled carbon nanotube dispersion and separation processes. In Phase I, the company demonstrated the feasibility of using the...

Biotech Naturale Inc. received a $256,000 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041) for the period of August 1, 2021 through July 31, 2022. The grant funds the development of a simple, targeted, and flexible method for transferring value-added genes from wild relatives of crop plants. The Engineering program seeks to improve quality of life and economic strength through fostering innovation...

The federal Project Grant award of $283,805 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of a novel cell-free, high-throughput platform to expedite the engineering of enzymes for biocatalytic "BioClick" reactions. The project, undertaken by Invizyne Technologies, Inc., a small disadvantaged business in Monrovia, CA, focuses on establishing an efficient cell-free protein...

Pumpkinseed Technologies Inc. received a $353,204 Phase I Small Business Innovation Research (SBIR) Project Grant award from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) on June 19, 2025, with completion targeted for April 30, 2026. The award funds development and proof-of-concept demonstration of Cell-MAPP (Cell Monitoring Against Presented Peptides), a novel technology that enables dynamic, real-time monitoring of individual T cell states during antigen...

Seedling Biosystems Inc. received a $179,086 Project Grant award dated September 15, 2025, under the Small Business Innovation Research (SBIR) Program / Small Business Technology Transfer (STTR) Program (CFDA 10.212), administered by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA). The award supports the company's development of Precision Germination, an innovative biotechnology platform that utilizes soybean seeds as mini-bioreactors to sustainably produce...

The U.S. National Science Foundation (NSF) awarded a $303,864 Phase I Small Business Innovation Research (SBIR) grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Core Biotherapeutics, Inc. (UEI N9FGZ15RQGJ4) located in Ladera Ranch, CA. The project aims to develop a platform for discovering therapeutic drug candidates that can modulate molecular networks driving diseases, with the potential to produce disease-modifying effects for neurodegenerative...

The Cooperative Agreement from the Department of Commerce National Institute of Standards and Technology's Science, Technology, Business and/or Education Outreach program (CFDA 11.620) provided $100,000 to Zymosense Inc. from August 1, 2021 through March 31, 2022. The funding supported Zymosense's work to develop automated aqueous two-phase extraction for low cost and scalable sorting of chiral-pure single walled carbon nanotubes. The Science, Technology, Business and/or Education Outreach...

New Horizon Biotech Inc. received a $256,000 National Science Foundation SBIR Phase I Project Grant to determine performance characteristics during cultivation of living organisms in a novel single-use horizontal modular and pressurizable microbial fermentor. The funding period is from February 15, 2021 through May 31, 2023 under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). This program seeks to advance science, engineering, and technology innovations to address...