Project Grant 80NSSC24K0321

The National Science Foundation (NSF) Division of Biological Infrastructure awarded the University of Oregon a $190,467 Project Grant under the Biological Sciences program (CFDA 47.074) to develop and evaluate non-cryogenic methods for preserving microbial samples in the field using heat-assisted desiccation. This research aims to enable researchers to survey a broader range of locations with reduced logistical challenges, as dried samples are lighter, safer, and easier to transport...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $306,852 to Mitegen, LLC to develop and validate cryopreservation technology for rapidly cooling and warming small biological samples such as oocytes, embryos, and other specimens. The award aims to automate cryopreservation processes, optimize convective cooling and warming rates, eliminate ice formation, and improve...

The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $710,128 Project Grant under the Biological Sciences (CFDA 47.074) program to The Research Foundation For The State University Of New York (SUNY) to conduct collaborative research on the "Energy Landscapes of Designed Cold Unfolding Proteins." The research aims to enhance understanding of the distinct three-dimensional shapes that proteins can adopt at extreme cold temperatures and high...

Cache DNA, Inc. was awarded a $255,819 National Science Foundation Technology, Innovation, and Partnerships Project Grant to develop a massively scalable storage solution for nucleic acids using barcoded polymer packets. The goal of the Phase I Small Business Innovation Research project is to establish a low-cost approach to maintaining the integrity of nucleic acids, including animal, bacterial, and viral genomes, at room temperature for decades without requiring energy-intensive freezing or...

This $801,972 National Science Foundation project grant funded quantitative molecular dynamics research on extremophile metalloproteins through 2026. The grant was awarded under the Biological Sciences program (CFDA 47.074) to the Seti Institute to study proteins from organisms thriving in extreme environments like high temperatures and pressures. The Seti Institute will lead experiments using novel synchrotron techniques like nuclear resonance vibrational spectroscopy and time domain...

This National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems Project Grant, CFDA 47.041, provides $452,847 to Rensselaer Polytechnic Institute (RPI) for research on protein behavior in microgravity environments. The funding will enable RPI to develop predictive models for how protein solutions flow and undergo structural changes in the absence of solid surfaces, to further fundamental science and industrial applications like pharmaceutical...

The National Institute of General Medical Sciences (NIGMS) awarded a $1,431,000 Project Grant to the Massachusetts Institute of Technology (MIT) to develop self-assembling nanomaterials that can protect microbes from processing, transportation, and storage stresses. The goal is to enable the production of important but challenging microbial therapeutics that are difficult to manufacture. The 3-year project, with an award date of September 18, 2023, aims to elucidate the mechanism by which...

This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $320,000 to Rensselaer Polytechnic Institute (RPI) from October 1, 2024 to September 30, 2028 to conduct research on crystal growth and particle self-assembly during directional solidification in microgravity conditions aboard the International Space Station (ISS). The research aims to reveal the mechanisms behind structure formation in materials by comparing the resulting...

This federal Project Grant award, with ID R01EB037456, was provided by the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program. The objective of the $545,682 award, with a performance period from February 1, 2025 to January 31, 2029, is to develop a molecular toolbox for non-invasive methods to precisely control programmed cell death pathways in animals using...

This three-year, $162,238 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research between Yale University, Stony Brook University, and researchers at examining and developing biomimetic peptides that inhibit ice formation. The researchers aim to understand and mimic antifreeze proteins in nature to generate synthetic antifreeze molecules for applications such as biological material preservation, food...