Early intervention to promote cardiovascular health of mothers and children in northern appalachia
Ended Cooperative Agreement Awarded Last action
- Award ID
- UG3HL162971
- Recipient
-
Pennsylvania State University UEI TNKGNDAWB445 Part of The Pennsylvania State University
- Awarding agency
-
National Heart Lung and Blood Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $1,527,494
Award facts
- Assistance listing
- 93.310 Trans-NIH Research Support
- Completion date
- Originally
- Funding agency
- Office of the Director National Institutes of Health, Department of Health and Human Services
- Place of performance
- Pennsylvania, USA
Award details come from USAspending.gov.
Description
- Abstract
- As part of nhlbi's enrich program, this research will test an implementation-ready intervention designed to improve cardiovascular health (CVH) among high risk mothers and young children during pregnancy and the first two years after delivery. Home visitation (HV) models meeting federal criteria of evidence of effectiveness will be leveraged to compare existing HV programs against those with an additional CVH intervention in a cluster-randomized, multicenter trial. Our multidisciplinary team has pioneered behavioral and lifestyle interventions for women during preconception and pregnancy and for infants during the first years after birth including those using HV for the primary prevention of obesity. We also have extensive research experience linking and integrating community- based healthcare programs with health system electronic medical records (emrs). For this proposal, we will collaborate with two nurse-family partnership agencies in northern appalachia, a medically underserved region with high rates of poverty and poor CVH, including high rates of obesity, heart disease, and tobacco use. We will enroll =500 of the 3000 pregnant women required for the UH3 phase multicenter trial. During the UG3 phase, we will pilot our proposed intervention with our community partners and work collaboratively with other enrich sites and nhlbi to develop the UH3 phase common protocol. Our proposed intervention incorporates tenets of social cognitive theory and the framework for understanding poverty using a skill-building curriculum that includes role modeling, goal-setting, and skill practice opportunities in the home. Five intervention pillars (lifestyle behaviors, self-regulation, responsive parenting, home environment, EMR integration) are designed to increase maternal knowledge and self-efficacy in their ability to establish healthy lifestyle habits and maternal parenting practices to improve CVH. Consistent with a hybrid trial type 1, the study design aims to understand the context for implementing the intervention. The composite primary outcome for mothers will be a modified version of the american heart association's life's simple 7 one year after childbirth; outcomes will also be assessed 2 years postpartum. The childhood primary outcome will be a composite of seven early life risk factors for poor CVH across with the final assessment at age 2 years. For these outcomes, the moderating effects of social determinants of health and psychosocial indices on outcomes will be explored. In addition, the context for implementation will be evaluated and factors influencing intervention efficacy will be identified to determine in HV, what works best, for whom, in which contexts, why and how. Lastly, we aim to lead network efforts to link and integrate HV summaries into emrs to allow for data sharing with healthcare providers to enhance intervention effectiveness so that the UH3 protocol can evaluate whether EMR integration with HV programs improves CVH composite indicators as well as health equity.
Transactions
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| Amendment | $601,401 | |
| Amendment | $62,500 | |
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| Amendment | $62,500 | |
| Amendment | $43,750 | |
| Amendment | $557,343 | |
| Amendment | $43,750 | |
| Original award | $43,750 |
Show all 29
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Kaiser Foundation Hospitals | $50,377 | |
| Upmc Home Healthcare Of Central Pennsylvania | $108,687 | |
| Geisinger Clinic | $137,046 | |
| Upmc Home Healthcare Of Central Pennsylvania | $106,918 | |
| Kaiser Foundation Hospitals | $50,377 | |
| The Research Foundation For The State University Of New York | $31,412 | |
| Geisinger Clinic | $137,046 |
Quick answers
Who received award UG3HL162971?
UG3HL162971 was awarded to Pennsylvania State University by National Heart Lung and Blood Institute (National Institutes of Health) on May 5, 2022.
How much is award UG3HL162971 worth?
$1,527,494 has been obligated on UG3HL162971.
Which agency awarded UG3HL162971?
National Heart Lung and Blood Institute (National Institutes of Health) awarded UG3HL162971, with funding from Office of the Director (National Institutes of Health).
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