Cooperative Agreement UF1AG094587
- The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $459,097 Project Grant to Pison Technology, Inc., a minority-owned small business in Boston, Massachusetts. The grant, awarded on June 12, 2025, will fund the development of a digital biomarker for amyotrophic lateral sclerosis (ALS) using Pison's wrist-worn neural biosensor device. The goal is to leverage the...
- This Project Grant award of $499,943 from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), supports the development of a novel, unobtrusive device by Aster Labs, Inc. to continuously measure and analyze gait patterns in older Black adults as an early indicator of health decline from Alzheimer's disease and related dementias (ADRD). The device aims to provide medical professionals and caregivers with remote access to these insights to help...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $506,399 Project Grant under the Aging Research Federal Grant Program (CFDA 93.866) to Healthy Design LTD. CO. to develop a novel continuous predictive wearable agitation monitor and alert system using actigraphy and AI for hospitalized older adults. The goal is to prevent delirium and dementia by closely monitoring agitation levels and enabling timely implementation of non-harmful...
- The Defense Health Agency awarded a $2,463,953 Project Grant to Biosensics LLC for the development of a "Wearable Sensor Platform for Remote Monitoring of Individuals on the Frontotemporal Dementia Spectrum." The award, made under the Military Medical Research and Development program (CFDA 12.420), will fund the creation of innovative wearable sensor technologies and cloud-based software solutions to enable remote monitoring and management of frontotemporal dementia and related...
- The National Institute on Aging (NIA), under the Federal Aging Research program (CFDA 93.866), awarded a $245,148 project grant to Eyenexo LLC to develop an automated rodent behavior testing system for non-invasively assessing early-stage Alzheimer's disease (AD). The project aims to develop a behavior biomarker that can differentiate AD from normal aging by studying defensive behaviors triggered by looming stimuli, which are linked to early AD pathology in the midbrain region. The 2-year...
- This $4,924,374 Project Grant award, with an initial term from September 1, 2025 to July 31, 2029, is provided by the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866). The award aims to validate novel biomarkers that capture the most relevant features of cognitive fluctuations in Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). The project will provide a multimodal characterization of the frequency and severity of cognitive...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $320,511 project grant to TRU Diagnostics Inc. to develop a novel diagnostic tool for chronic diseases. The project aims to create a "non-stochastic W function epigenomic roadmap" using systems-based dynamic modeling to capture the shifting homeostatic set points of epigenetic markers over time. This transformative approach aims to enable personalized, dynamic health forecasts...
- The National Institute on Aging (NIA) awarded a $780,466 Project Grant (CFDA 93.866 Aging Research) to The Regents of the University of Colorado, doing business as the University of Colorado-Denver, with a period of performance from December 15, 2024 to November 30, 2029. The goal of this project is to develop digital biomarkers using single-channel sleep electroencephalography (EEG) to monitor brain health and detect pathological aging and early neurodegenerative changes, such as those seen...
- The National Institute on Aging (NIA) awarded a $154,748 Project Grant under the Aging Research program (CFDA 93.866) to Brigham & Women's Hospital Inc. to develop an ultrasensitive blood-based diagnostic tool for accurately determining the presence and severity of Alzheimer's disease (AD). The project aims to utilize single molecule detection to measure low abundance AD protein biomarkers, particularly phosphorylated tau proteins, in blood extracellular vesicles, which can reflect protein...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $493,964 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Aromha Inc. on September 10, 2025. The grant will fund the development and evaluation of a digital, self-administered, multilingual olfactory test battery called the AROMHA Brain Health Test. The goal is to create an at-home screening tool to detect early signs of Lewy body disease, which is present in up...
The U.S. National Institute on Aging (NIA) awarded a $5,174,076 Cooperative Agreement grant under the Aging Research program (CFDA 93.866) to Biosensics LLC, a small business in Newton, Massachusetts. The purpose of the grant is to develop and qualify digital biomarkers to monitor motor function in individuals with Progressive Supranuclear Palsy (PSP) and Dementia with Lewy Bodies (DLB) using wearable sensor technologies. Specifically, the project will utilize Biosensics' PAMSYS and PAMSYS ULM wearable sensor platforms to comprehensively monitor upper and lower limb function in these neurodegenerative conditions. The goal is to validate these digital monitoring biomarkers through the FDA Biomarker Qualification Program. The grant period runs from September 1, 2025 to August 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $5.2m | 8/28/25 |