Cooperative Agreement U44NS119974

Federal Grant Award Summary Cooltech, LLC received a $983,042 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop MI-Helper, a thermodynamic neuromodulation device for migraine treatment. The award, dated September 17, 2025, with a completion date of August 31, 2027, supports the advancement of this novel, non-pharmaceutical...

This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), provides $721,428.00 in funding to the University of Pittsburgh to conduct a mechanistic neuroimaging study on the effects of auricular stimulation and auriculotherapy in healthy volunteers and chronic low back pain patients. The key objectives are to: 1) use functional near-infrared spectroscopy (fNIRS)...

Cooler Heads Care, Inc. was awarded a $632,981.28 Project Grant from the National Cancer Institute's Cancer Cause and Prevention Research program (CFDA 93.393) to develop a portable, patient-administered scalp cooling device and smartphone application. The goal is to reduce barriers to scalp cooling access for chemotherapy patients experiencing hair loss. Cooler Heads will develop training materials and conduct usability testing to demonstrate patients can self-administer the scalp cooling...

Summary Children's Mercy Hospital received a $1.51 million Project Grant from the National Center for Complementary and Integrative Health under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), awarded on September 22, 2025, with completion targeted for August 31, 2028. The grant funds a feasibility trial evaluating Immersive Neurofeedback Self-Regulation Training (INSERT), a home-based mind-body intervention combining wearable electroencephalogram (EEG)...

Federal Project Grant Award Summary The University of Southern California received a $415,000 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective February 15, 2026, with a completion date of January 31, 2031. The award supports fundamental neuroscience research investigating the cellular mechanisms of cold allodynia in the...

The National Institutes of Health National Center for Complementary and Integrative Health awarded New York University $785,637 under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) from June 2021 through May 2025. This Cooperative Agreement will support the development and pilot testing of telephone-delivered and video-based Mindfulness-Based Cognitive Therapy (MBCT) protocols for patients with migraine headaches and depressive symptoms. Specifically, the...

Emergency Medical Innovation LLC received a $256,000 Project Grant award from the National Science Foundation to develop a nasal compression device with medicated intranasal sponges for treating nosebleeds. Funded through the NSF's Engineering program (CFDA 47.041), the award will support design and testing of a nasal clip capable of consistently applying proper pressure levels and eluting appropriate doses of medication for nosebleed treatment when placed nominally. Over the one-year period...

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $419,375.00 to support research on the role of the GPR37L1 receptor in chronic migraine. The funding will enable a research team at Florida Atlantic University, with a sub-award to the University of Florida, to conduct a comprehensive investigation into the involvement of GPR37L1 signaling in the neuropathology of...

Federal Project Grant Award Summary New York Institute of Technology received a $472,592 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded August 1, 2025, with a completion date of July 31, 2028. The award funds preclinical research and development of RGIA5474, a novel α9α10 nicotinic acetylcholine receptor (nAChR) antagonist, to evaluate...

Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $415,249 to the Regents of the University of Michigan on August 7, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This Project Grant supports a two-year research initiative (through July 31, 2027) to develop predictive measures for migraine attack onset through continuous monitoring of autonomic nervous system...